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Fig. 4 | Particle and Fibre Toxicology

Fig. 4

From: Establishing relationships between particle-induced in vitro and in vivo inflammation endpoints to better extrapolate between in vitro markers and in vivo fibrosis

Fig. 4

Relationship between PMN influx in vivo and lung fibrotic histopathology score following exposure to α-quartz. The α-quartz used in the source studies was Min-U-sil® 5. Blue dots are data entries where the PMN influx was recorded following a period of post-exposure conditioning (36 days), whereas red dots represent PMN influx values collected with no post-exposure conditioning time (< 48 h). Data points given are mean fibrotic score ± SEM (N = 5–6) [27, 28, 32, 40]

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