Fig. 4From: Establishing relationships between particle-induced in vitro and in vivo inflammation endpoints to better extrapolate between in vitro markers and in vivo fibrosisRelationship between PMN influx in vivo and lung fibrotic histopathology score following exposure to α-quartz. The α-quartz used in the source studies was Min-U-sil® 5. Blue dots are data entries where the PMN influx was recorded following a period of post-exposure conditioning (36 days), whereas red dots represent PMN influx values collected with no post-exposure conditioning time (< 48 h). Data points given are mean fibrotic score ± SEM (N = 5–6) [27, 28, 32, 40]Back to article page