Fig. 1From: Polycyclic aromatic hydrocarbons in urban particle matter exacerbate movement disorder after ischemic stroke via potentiation of neuroinflammationMicroglial activation induced by intranasal administration of CRM28. CRM28 was suspended in water and intranasally (i.n.) administered at doses of 0, 10 or 100 µg/mouse once a day for 7 days. Brain slices were stained with Iba1 and CD68 and observed by confocal microscopy. A Representative stained pictures of the olfactory bulb. B Amoeboid scores. C The CD68-stained area of the olfactory bulb. The values are presented as the mean ± S.D. (n = 6 animals in each group). The data were analyzed using one-way ANOVA [B F(2, 15) = 4.524, p = 0.0290, C F(2, 15) = 6.770, p = 0.0080] followed by Dunnett’s multiple comparisons test. D Representative stained pictures of the cerebral cortex. E Amoeboid scores. F The CD68-stained area of the cerebral cortex. The values are presented as the mean ± S.D. (n = 6 animals in each group). The data were analyzed using one-way ANOVA [E: F(2, 15) = 9.860, p = 0.0018, F: F(2, 15) = 21.83, p < 0.0001] followed by Dunnett’s multiple comparisons testBack to article page