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Fig. 2 | Particle and Fibre Toxicology

Fig. 2

From: ROS generation and p-38 activation contribute to montmorillonite-induced corneal toxicity in vitro and in vivo

Fig. 2

Cytotoxicity of montmorillonite (Mt) with different properties in HCEC-B4G12 cells. HCEC-B4G12 cells were treated with various concentrations (1.56–100 μg/mL) of five types of Mt for 24 h (A, C and E) and 48 h (B, D and F) before the measurements. A, B Effects on the ATP content of HCEC-B4G12 cells. C, D Cell viability examined using the CCK-8 assay. E, F Effects on membrane integrity of HCEC-B4G12 cells based on the LDH assay. Data points are the mean ± SD from three independent experiments with three parallel samples per concentration in each experiment. *p < 0.05 compared with the control

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