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Fig. 8 | Particle and Fibre Toxicology

Fig. 8

From: Decidual derived exosomal miR-99a-5p targets Ppp2r5a to inhibit trophoblast invasion in response to CeO2NPs exposure

Fig. 8

Diagram of the mechanism of action of CeO2NPs exposure during pregnancy leading to impaired trophoblast invasion by altering the genetic composition of decidual-derived exosomes. CeO2NPs exposure can inhibit trophoblast invasion by upregulating miR-99a-5p expression in decidual -derived exosomes and downregulating PPP2R5A expression therein after uptake by trophoblast cells

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Particle and Fibre Toxicology

ISSN: 1743-8977

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