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Fig. 4 | Particle and Fibre Toxicology

Fig. 4

From: Single inhalation exposure to polyamide micro and nanoplastic particles impairs vascular dilation without generating pulmonary inflammation in virgin female Sprague Dawley rats

Fig. 4

Vascular reactivity in the abdominal aorta and uterine artery was assessed by establishing concentration response curves with the endothelial-dependent vasodilator methacholine (A and D), the endothelial-independent vasodilator sodium nitroprusside (B and E), and the vasoconstrictor phenylephrine (C and F). Significance was assessed by comparing overall reactivity via a four-parameter nonlinear regression analysis. Data are presented as mean ± SEM, n = 9–11, *Significantly different (p < 0.05) from filtered air controls

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