Fig. 4From: Single inhalation exposure to polyamide micro and nanoplastic particles impairs vascular dilation without generating pulmonary inflammation in virgin female Sprague Dawley ratsVascular reactivity in the abdominal aorta and uterine artery was assessed by establishing concentration response curves with the endothelial-dependent vasodilator methacholine (A and D), the endothelial-independent vasodilator sodium nitroprusside (B and E), and the vasoconstrictor phenylephrine (C and F). Significance was assessed by comparing overall reactivity via a four-parameter nonlinear regression analysis. Data are presented as mean ± SEM, n = 9–11, *Significantly different (p < 0.05) from filtered air controlsBack to article page