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Fig. 1 | Particle and Fibre Toxicology

Fig. 1

From: Uncovering the Fate and Risks of Intravenously Injected Prussian Blue Nanoparticles in mice by an Integrated Methodology of Toxicology, Pharmacokinetics, Proteomics, and Metabolomics

Fig. 1

Characterization of PB NPs and toxicological evaluations of mice with different injections of PB NPs. (a) TEM micrograph of PB NPs. (b) UV‒Vis absorption of PB NPs. (c) XRD spectrum of PB NPs. (d) FTIR spectrum of PB NPs. (e) Hematological and biochemical parameters of mice treated with different doses of PB NPs. Annotation: WBC-white blood cell, MON-monocyte, GRA-granulocyte, LYM-lymphocyte, RBC-red blood cell, HGB-haemoglobin, PLT-platelet. Liver function parameters: ALP-alkaline phosphatase, AST-glutamic oxaloacetic transaminase, ALT-glutamic pyruvic transaminase. Kidney function parameters: BUN-blood urea nitrogen, CRE-creatinine. The red dashed line represents the normal range. (f) Organ coefficients of mice treated with different doses of PB NPs.

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