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Fig. 5 | Particle and Fibre Toxicology

Fig. 5

From: Uncovering the Fate and Risks of Intravenously Injected Prussian Blue Nanoparticles in mice by an Integrated Methodology of Toxicology, Pharmacokinetics, Proteomics, and Metabolomics

Fig. 5

Proteomics and metabolomics analysis of mouse livers after i.v. administration of 20 mg/kg PB NPs. (a) Venn diagram of differentially expressed proteins in the liver. (blue: 7th day, pink: 60th day) (b) KEGG pathway enrichment analysis of differentially expressed proteins in the livers on the 7th day. (c) OPLS-DA score plot of the liver metabolome. (d) Venn diagram of changed metabolites in the livers (blue: 7th day, pink: 60th day). (e-f) KEGG pathway enrichment analysis of the changed metabolites in the livers on the 7th day (e) and the 60th day (f)

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