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Fig. 1 | Particle and Fibre Toxicology

Fig. 1

From: MMP-3-mediated cleavage of OPN is involved in copper oxide nanoparticle-induced activation of fibroblasts

Fig. 1

Cytotoxicity of Nano-CuO on BEAS-2B cells, U937-derived macrophages (U937*), and MRC-5 fibroblasts. BEAS-2B (a), U937* macrophages (b), and MRC-5 fibroblasts (c) were seeded into 96-well plates and treated with 0.5, 1, 2, 5, and 10 µg/mL of Nano-CuO for 24 h (a and b) and 48 h (c), respectively. Cells without treatment were used as control. The cytotoxicity was determined by alamarBlue assay. Data represent mean ± SE (n = 6). * Significant difference as compared to the control group, p < 0.05

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