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  1. With the development of zinc oxide nanoparticles (ZnO NPs) in the field of nanotechnology, their toxicological effects are attracting increasing attention, and the mechanisms for ZnO NPs neurotoxicity remain o...

    Authors: Zixuan Liu, Xuying Lv, Lei Xu, Xuting Liu, Xiangyu Zhu, Erqun Song and Yang Song
    Citation: Particle and Fibre Toxicology 2020 17:46
  2. Nanoparticles exhibit a specific diffusion and sedimentation behavior under cell culture conditions as used in nantoxicological in vitro testing. How a particular particle suspension behaves depends on the par...

    Authors: Falko Frenzel, Laura König-Mattern, Valerie Stock, Linn Voss, Maxi B. Paul, Holger Sieg, Albert Braeuning, Andreas Voigt and Linda Böhmert
    Citation: Particle and Fibre Toxicology 2020 17:45
  3. Accurate knowledge of cell−/tissue-delivered dose plays a pivotal role in inhalation toxicology studies, since it is the key parameter for hazard assessment and translation of in vitro to in vivo dose-response...

    Authors: Yaobo Ding, Patrick Weindl, Anke-Gabriele Lenz, Paula Mayer, Tobias Krebs and Otmar Schmid
    Citation: Particle and Fibre Toxicology 2020 17:44
  4. The quantification of nanomaterials accumulated in various organs is crucial in studying their toxicity and toxicokinetics. However, some types of nanomaterials, including carbon nanomaterials (CNMs), are diff...

    Authors: Dong-Keun Lee, Soyeon Jeon, Jiyoung Jeong, Kyung Seuk Song and Wan-Seob Cho
    Citation: Particle and Fibre Toxicology 2020 17:43
  5. The toxicity of released metallic particles generated in metal-on-metal (MoM) total hip arthroplasty (THA) using cobalt chromium (CoCr) has raised concerns regarding their safety amongst both surgeons and the ...

    Authors: Jing Xu, Junyao Yang, Jian Chen, Xiaoli Zhang, Yuanhao Wu, Alister Hart, Agata Nyga and Julia C. Shelton
    Citation: Particle and Fibre Toxicology 2020 17:42
  6. Particulate matters (PMs) in ambient air pollution are closely related to the incidence of respiratory diseases and decreased lung function. Our previous report demonstrated that PMs-induced oxidative stress i...

    Authors: Yu-Chen Chen, Tzu-Yi Chuang, Chen-Wei Liu, Chi-Wei Liu, Tzu-Lin Lee, Tsai-Chun Lai and Yuh-Lien Chen
    Citation: Particle and Fibre Toxicology 2020 17:41
  7. Engineered nanomaterials are increasingly being incorporated into synthetic materials as fillers and additives. The potential pathological effects of end-of-lifecycle recycling and disposal of virgin and nano-...

    Authors: Jayme P. Coyle, Raymond C. Derk, Tiffany G. Kornberg, Dilpreet Singh, Jake Jensen, Sherri Friend, Robert Mercer, Todd A. Stueckle, Philip Demokritou, Yon Rojanasakul and Liying W. Rojanasakul
    Citation: Particle and Fibre Toxicology 2020 17:40
  8. Respirable crystalline silica causes lung carcinomas and many thousand future cancer cases are expected in e.g. Europe. Critical questions are how silica causes genotoxicity in the respiratory epithelium and i...

    Authors: Rongrong Wu, Johan Högberg, Mikael Adner, Patricia Ramos-Ramírez, Ulla Stenius and Huiyuan Zheng
    Citation: Particle and Fibre Toxicology 2020 17:39
  9. Diesel exhaust is carcinogenic and exposure to diesel particles cause health effects. We investigated the toxicity of diesel exhaust particles designed to have varying physicochemical properties in order to at...

    Authors: Katja Maria Bendtsen, Louise Gren, Vilhelm Berg Malmborg, Pravesh Chandra Shukla, Martin Tunér, Yona J. Essig, Annette M. Krais, Per Axel Clausen, Trine Berthing, Katrin Loeschner, Nicklas Raun Jacobsen, Henrik Wolff, Joakim Pagels and Ulla Birgitte Vogel
    Citation: Particle and Fibre Toxicology 2020 17:38
  10. Pneumococcus is one of the most common human airway pathogens that causes life-threatening infections. Ambient fine particulate matter (PM) with aerodynamic diameter ≤ 2.5 μm (PM2.5) is known to significantly con...

    Authors: Yu-Wen Chen, Mei-Zi Huang, Chyi-Liang Chen, Chieh-Ying Kuo, Chia-Yu Yang, Chuan Chiang-Ni, Yi-Ywan M. Chen, Chia-Ming Hsieh, Hui-Yu Wu, Ming-Ling Kuo, Cheng-Hsun Chiu and Chih-Ho Lai
    Citation: Particle and Fibre Toxicology 2020 17:37
  11. Exposure to air pollution has been associated with adverse effects on human health, and ultimately increased morbidity and mortality. This is predominantly due to hazardous effects on the cardiovascular system...

    Authors: Siri A. N. Holme, Torben Sigsgaard, Jørn A. Holme and Gitte Juel Holst
    Citation: Particle and Fibre Toxicology 2020 17:36
  12. Air pollution is killing close to 5 million people a year, and harming billions more. Air pollution levels remain extremely high in many parts of the world, and air pollution-associated premature deaths have b...

    Authors: Irini M. Dijkhoff, Barbara Drasler, Bedia Begum Karakocak, Alke Petri-Fink, Giuseppe Valacchi, Marc Eeman and Barbara Rothen-Rutishauser
    Citation: Particle and Fibre Toxicology 2020 17:35
  13. Nanotechnology is indispensable to many different applications. Although nanoparticles have been widely used in, for example, cosmetics, sunscreen, food packaging, and medications, they may pose human safety r...

    Authors: Min Beom Heo, Minjeong Kwak, Kyu Sup An, Hye Jin Kim, Hyeon Yeol Ryu, So Min Lee, Kyung Seuk Song, In Young Kim, Ji-Hwan Kwon and Tae Geol Lee
    Citation: Particle and Fibre Toxicology 2020 17:34
  14. In their Commentary Saber et al. (Part Fibre Toxicol 16: 44, 2019) argue that chronic inhalation studies in rats can be used for assessing the lung cancer risk of insoluble nanomaterials. The authors make seve...

    Authors: Kevin E. Driscoll, Paul A. Borm, Ishrat Chaudhuri, Len Levy, Mei Yong, David Warheit, Robert McCunney and Günter Oberdörster
    Citation: Particle and Fibre Toxicology 2020 17:33
  15. In response to the Letter to the Editor by Kevin Driscoll et al., we certainly agree that particle clearance halftimes are increased with increasing lung burden in rats, hamsters and mice, whereas complete inh...

    Authors: Anne T. Saber, Sarah S. Poulsen, Niels Hadrup, Nicklas R. Jacobsen and Ulla Vogel
    Citation: Particle and Fibre Toxicology 2020 17:32
  16. Epidemiological and animal studies provide compelling indications that environmental and engineered nanomaterials (NMs) pose a risk for pregnancy, fetal development and offspring health later in life. Understa...

    Authors: Battuja Batbajar Dugershaw, Leonie Aengenheister, Signe Schmidt Kjølner Hansen, Karin Sørig Hougaard and Tina Buerki-Thurnherr
    Citation: Particle and Fibre Toxicology 2020 17:31
  17. Graphene quantum dots (GQDs) provide a bright prospect in the biomedical application because they contain low-toxic compounds and promise imaging of deep tissues and tiny vascular structures. However, the bios...

    Authors: Tianshu Wu, Xue Liang, Xi Liu, Yimeng Li, Yutong Wang, Lu Kong and Meng Tang
    Citation: Particle and Fibre Toxicology 2020 17:30
  18. Particle matter (PM) has been associated with increased morbidity and mortality rates across the world. This study was designed to test the hypotheses that pyrotechnic firework displays introduce significant a...

    Authors: Christina Hickey, Christopher Gordon, Karen Galdanes, Martin Blaustein, Lori Horton, Steven Chillrud, James Ross, Lital Yinon, Lung Chi Chen and Terry Gordon
    Citation: Particle and Fibre Toxicology 2020 17:28
  19. Commercial uranium mining on the Navajo Nation has subjected communities on tribal lands in the Southwestern United States to exposures from residual environmental contamination. Vascular health effects from t...

    Authors: Bethany Sanchez, Xixi Zhou, Amy S. Gardiner, Guy Herbert, Selita Lucas, Masako Morishita, James G. Wagner, Ryan Lewandowski, Jack R. Harkema, Chris Shuey, Matthew J. Campen and Katherine E. Zychowski
    Citation: Particle and Fibre Toxicology 2020 17:29
  20. Wood combustion emissions have been studied previously either by in vitro or in vivo models using collected particles, yet most studies have neglected gaseous compounds. Furthermore, a more accurate and holist...

    Authors: Tuukka Ihantola, Sebastiano Di Bucchianico, Mikko Happo, Mika Ihalainen, Oskari Uski, Stefanie Bauer, Kari Kuuspalo, Olli Sippula, Jarkko Tissari, Sebastian Oeder, Anni Hartikainen, Teemu J. Rönkkö, Maria-Viola Martikainen, Kati Huttunen, Petra Vartiainen, Heikki Suhonen…
    Citation: Particle and Fibre Toxicology 2020 17:27
  21. Food-grade TiO2 (E171 in the EU) is widely used as a coloring agent in foodstuffs, including sweets. Chronic dietary exposure raises concerns for human health due to proinflammatory properties and the ability to ...

    Authors: Christine Coméra, Christel Cartier, Eric Gaultier, Olivier Catrice, Quentin Panouille, Sarah El Hamdi, Kristof Tirez, Inge Nelissen, Vassilia Théodorou and Eric Houdeau
    Citation: Particle and Fibre Toxicology 2020 17:26
  22. Epidemiologic studies have suggested that elevated concentrations of particulate matter (PM) are strongly associated with an increased risk of developing cardiovascular diseases, including arrhythmia. However,...

    Authors: Sujin Ju, Leejin Lim, Han-Yi Jiao, Seok Choi, Jae Yeoul Jun, Young-Jae Ki, Dong-Hyun Choi, Ji yi Lee and Heesang Song
    Citation: Particle and Fibre Toxicology 2020 17:25
  23. Given the global abundance and environmental persistence, exposure of humans and (aquatic) animals to micro- and nanoplastics is unavoidable. Current evidence indicates that micro- and nanoplastics can be take...

    Authors: Minne Prüst, Jonelle Meijer and Remco H. S. Westerink
    Citation: Particle and Fibre Toxicology 2020 17:24
  24. Wide applications of nanoparticles (NPs) have raised increasing concerns about safety to humans. Oxidative stress and inflammation are extensively investigated as mechanisms for NPs-induced toxicity. Autophagy...

    Authors: Mingxiang Wang, Jin Li, Shunni Dong, Xiaobo Cai, Aili Simaiti, Xin Yang, Xinqiang Zhu, Jianhong Luo, Lin-Hua Jiang, Binyang Du, Peilin Yu and Wei Yang
    Citation: Particle and Fibre Toxicology 2020 17:23
  25. Caloric restriction (CR) is known to improve health and extend lifespan in human beings. The effects of CR on adverse health outcomes in response to particulate matter (PM) exposure and the underlying mechanis...

    Authors: Daochuan Li, Shen Chen, Qiong Li, Liping Chen, Haiyan Zhang, Huiyao Li, Dianke Yu, Rong Zhang, Yujie Niu, Shaoyou Lu, Lizhu Ye, Xiaowen Zeng, Guanghui Dong, Rui Chen, Michael Aschner, Yuxin Zheng…
    Citation: Particle and Fibre Toxicology 2020 17:22
  26. There is a steadily increasing quantity of silver nanoparticles (AgNP) produced for numerous industrial, medicinal and private purposes, leading to an increased risk of inhalation exposure for both professiona...

    Authors: Wolfgang G. Kreyling, Uwe Holzwarth, Stephanie Hirn, Carsten Schleh, Alexander Wenk, Martin Schäffler, Nadine Haberl and Neil Gibson
    Citation: Particle and Fibre Toxicology 2020 17:21
  27. Talc, a hydrous magnesium silicate, often used for genital hygiene purposes, is associated with ovarian carcinoma in case-control studies. Its potential to cause inflammation, injury, and functional changes in...

    Authors: Erika Sato, Sandra A. McDonald, Yuwei Fan, Shaina Peterson, Joseph D. Brain and John J. Godleski
    Citation: Particle and Fibre Toxicology 2020 17:20
  28. In food toxicology, there is growing interest in studying the impacts of foodborne nanoparticles (NPs, originating from food additives, food supplements or food packaging) on the intestinal microbiome due to t...

    Authors: Bruno Lamas, Natalia Martins Breyner and Eric Houdeau
    Citation: Particle and Fibre Toxicology 2020 17:19
  29. The adverse effects of air pollutants including particulate matter (PM) on the central nervous system is increasingly reported by epidemiological, animal and post-mortem studies in the last decade. Oxidative s...

    Authors: Sweelin Chew, Riikka Lampinen, Liudmila Saveleva, Paula Korhonen, Nikita Mikhailov, Alexandra Grubman, Jose M. Polo, Trevor Wilson, Mika Komppula, Teemu Rönkkö, Cheng Gu, Alan Mackay-Sim, Tarja Malm, Anthony R. White, Pasi Jalava and Katja M. Kanninen
    Citation: Particle and Fibre Toxicology 2020 17:18
  30. Emissions from road traffic are under constant discussion since they pose a major threat to human health despite the increasingly strict emission targets and regulations. Although the new passenger car regulat...

    Authors: Henri Hakkarainen, Päivi Aakko-Saksa, Maija Sainio, Tuukka Ihantola, Teemu J. Rönkkö, Päivi Koponen, Topi Rönkkö and Pasi I. Jalava
    Citation: Particle and Fibre Toxicology 2020 17:17
  31. Toxicity testing and regulation of advanced materials at the nanoscale, i.e. nanosafety, is challenged by the growing number of nanomaterials and their property variants requiring assessment for potential huma...

    Authors: Sabina Halappanavar, Sybille van den Brule, Penny Nymark, Laurent Gaté, Carole Seidel, Sarah Valentino, Vadim Zhernovkov, Pernille Høgh Danielsen, Andrea De Vizcaya, Henrik Wolff, Tobias Stöger, Andrey Boyadziev, Sarah Søs Poulsen, Jorid Birkelund Sørli and Ulla Vogel
    Citation: Particle and Fibre Toxicology 2020 17:16
  32. Silica nanoparticles (nanoSiO2) are promising systems that can deliver biologically active compounds to tissues such as the heart in a controllable manner. However, cardiac toxicity induced by nanoSiO2 has been r...

    Authors: Omar Lozano, Christian Silva-Platas, Héctor Chapoy-Villanueva, Baruc E. Pérez, Jarmon G. Lees, Chrishan J. A. Ramachandra, Flavio F. Contreras-Torres, Anay Lázaro-Alfaro, Estefanía Luna-Figueroa, Judith Bernal-Ramírez, Aldemar Gordillo-Galeano, Alfredo Benitez, Yuriana Oropeza-Almazán, Elena C. Castillo, Poh Ling Koh, Derek J. Hausenloy…
    Citation: Particle and Fibre Toxicology 2020 17:15
  33. Emerging evidence supports ambient fine particulate matter (PM2.5) exposure is associated with insulin resistance (IR) and hepatic lipid accumulation. In this study, we aimed to evaluate the sex-dependent vulnera...

    Authors: Ran Li, Qing Sun, Sin Man Lam, Rucheng Chen, Junyao Zhu, Weijia Gu, Lu Zhang, He Tian, Kezhong Zhang, Lung-Chi Chen, Qinghua Sun, Guanghou Shui and Cuiqing Liu
    Citation: Particle and Fibre Toxicology 2020 17:14
  34. Silica nanoparticles (SiNPs) are among the most widely manufactured and used nanoparticles. Concerns about potential health effects of SiNPs have therefore risen. Using a 3D tri-culture model of the alveolar l...

    Authors: Tonje Skuland, Marit Låg, Arno C. Gutleb, Bendik C. Brinchmann, Tommaso Serchi, Johan Øvrevik, Jørn A. Holme and Magne Refsnes
    Citation: Particle and Fibre Toxicology 2020 17:13
  35. The growing use of silica nanoparticles (SiNPs) in many fields raises human toxicity concerns. We studied the toxicity of SiNP-20 (particle diameter 20 nm) and SiNP-100 (100 nm) and the underlying mechanisms w...

    Authors: De-Ping Wang, Zhao-Jun Wang, Rong Zhao, Cai-Xia Lin, Qian-Yu Sun, Cai-Ping Yan, Xin Zhou and Ji-Min Cao
    Citation: Particle and Fibre Toxicology 2020 17:12
  36. Silver nanoparticles (AgNPs) are used extensively in various consumer products because of their antimicrobial potential. This requires insight in their potential hazards and risks including adverse effects dur...

    Authors: Ashraf Abdelkhaliq, Meike van der Zande, Ruud J. B. Peters and Hans Bouwmeester
    Citation: Particle and Fibre Toxicology 2020 17:11
  37. The terms agglomerates and aggregates are frequently used in the regulatory definition(s) of nanomaterials (NMs) and hence attract attention in view of their potential influence on health effects. However, the...

    Authors: Sivakumar Murugadoss, Frederic Brassinne, Noham Sebaihi, Jasmine Petry, Stevan M. Cokic, Kirsten L. Van Landuyt, Lode Godderis, Jan Mast, Dominique Lison, Peter H. Hoet and Sybille van den Brule
    Citation: Particle and Fibre Toxicology 2020 17:10
  38. Epidemiological studies have reported associations between elevated air pollution and autism spectrum disorders (ASD). However, we hypothesized that exposure to air pollution that mimics real world scenarios, ...

    Authors: Baharan Emam, Abbas Shahsavani, Fariba Khodagholi, Saeed Motesaddi Zarandi, Philip K. Hopke, Mostafa Hadei, Hamidreza Behbahani and Maryam Yarahmadi
    Citation: Particle and Fibre Toxicology 2020 17:8
  39. Using engineered nanomaterial-based toners, laser printers generate aerosols with alarming levels of nanoparticles that bear high bioactivity and potential health risks. Yet, the cardiac impacts of printer-emi...

    Authors: Alex P. Carll, Renata Salatini, Sandra V. Pirela, Yun Wang, Zhengzhi Xie, Pawel Lorkiewicz, Nazratan Naeem, Yong Qian, Vincent Castranova, John J. Godleski and Philip Demokritou
    Citation: Particle and Fibre Toxicology 2020 17:7
  40. Li-ion batteries (LIB) are used in most portable electronics. Among a wide variety of materials, LiCoO2 (LCO) is one of the most used for the cathode of LIB. LCO particles induce oxidative stress in mouse lungs d...

    Authors: Violaine Sironval, Vittoria Scagliarini, Sivakumar Murugadoss, Maura Tomatis, Yousof Yakoub, Francesco Turci, Peter Hoet, Dominique Lison and Sybille van den Brule
    Citation: Particle and Fibre Toxicology 2020 17:6
  41. Although biocides at low concentrations have been used to control pests, they can be more harmful than industrial chemicals as humans are directly and frequently exposed to such biocides. Benzalkonium chloride...

    Authors: Hye-Yeon Choi, Yong-Hoon Lee, Cheol-Hong Lim, Yong-Soon Kim, In-Seop Lee, Ji-Min Jo, Ha-Young Lee, Hyo-Geun Cha, Hee Jong Woo and Dong-Seok Seo
    Citation: Particle and Fibre Toxicology 2020 17:5
  42. Carbonaceous aerosols emitted from indoor and outdoor biomass burning are major risk factors contributing to the global burden of disease. Wood tar aerosols, namely, tar ball particles, compose a substantial f...

    Authors: Michal Pardo, Chunlin Li, Quanfu He, Smadar Levin-Zaidman, Michael Tsoory, Qingqing Yu, Xinming Wang and Yinon Rudich
    Citation: Particle and Fibre Toxicology 2020 17:4
  43. Fibrous chrysotile has been the most commonly applied asbestos mineral in a range of technical applications. However, it is toxic and carcinogenic upon inhalation. The chemical reactivity of chrysotile fiber s...

    Authors: Martin Walter, Walter D. C. Schenkeveld, Gerald Geroldinger, Lars Gille, Michael Reissner and Stephan M. Kraemer
    Citation: Particle and Fibre Toxicology 2020 17:3
  44. Previous studies have shown that inhalation of welding fumes may induce pulmonary and systemic inflammation and organ accumulation of metal, to which spermatogenesis and endocrine function may be sensitive. Al...

    Authors: Astrid Skovmand, Aaron Erdely, James M. Antonini, Timothy R. Nurkiewicz, Mohammad Shoeb, Tracy Eye, Vamsi Kodali, Katrin Loeschner, Janja Vidmar, Jørgen S. Agerholm, Sandra Goericke-Pesch, Ulla Vogel and Karin S. Hougaard
    Citation: Particle and Fibre Toxicology 2020 17:2
  45. The regulatory definition(s) of nanomaterials (NMs) frequently uses the term ‘agglomerates and aggregates’ (AA) despite the paucity of evidence that AA are significantly relevant from a nanotoxicological persp...

    Authors: Sivakumar Murugadoss, Sybille van den Brule, Frederic Brassinne, Noham Sebaihi, Jorge Mejia, Stéphane Lucas, Jasmine Petry, Lode Godderis, Jan Mast, Dominique Lison and Peter H. Hoet
    Citation: Particle and Fibre Toxicology 2020 17:1
  46. Due to its excellent physicochemical properties and wide applications in consumer goods, titanium dioxide nanoparticles (TiO2 NPs) have been increasingly exposed to the environment and the public. However, the he...

    Authors: Zhangjian Chen, Di Zhou, Shuo Han, Shupei Zhou and Guang Jia
    Citation: Particle and Fibre Toxicology 2019 16:48
  47. Zinc oxide nanoparticles (ZnO-NPs) are widely used in many industrial sectors and previous studies have reported that exposure of the lungs to ZnO-NPs induces both acute and/or chronic pulmonary inflammation, ...

    Authors: Radwa Sehsah, Wenting Wu, Sahoko Ichihara, Naozumi Hashimoto, Yoshinori Hasegawa, Cai Zong, Ken Itoh, Masayuki Yamamoto, Ahmed Ali Elsayed, Soheir El-Bestar, Emily Kamel and Gaku Ichihara
    Citation: Particle and Fibre Toxicology 2019 16:47
  48. Silver nanoparticles (AgNPs), as promising anti-microbials and anti-cancer therapeutics, the toxicological effect and killing efficiency towards cells need in-depth investigation for better applications in dai...

    Authors: Ming Xu, Qiuyuan Yang, Lining Xu, Ziyu Rao, Dong Cao, Ming Gao and Sijin Liu
    Citation: Particle and Fibre Toxicology 2019 16:46
  49. A growing body of epidemiological literature indicates that particulate matter (PM) air pollution exposure is associated with elevated Alzheimer’s disease (AD) risk and may exacerbate AD-related cognitive decl...

    Authors: Katrina Jew, Denise Herr, Candace Wong, Andrea Kennell, Keith Morris-Schaffer, Günter Oberdörster, M. Kerry O’Banion, Deborah A. Cory-Slechta and Alison Elder
    Citation: Particle and Fibre Toxicology 2019 16:45
  50. Recently, Borm and Driscoll published a commentary discussing grouping of Poorly Soluble particles of Low Toxicity (PSLTs) and the use of rats as an animal model for human hazard assessment of PSLTs (Particle ...

    Authors: Anne T. Saber, Sarah S. Poulsen, Niels Hadrup, Nicklas R. Jacobsen and Ulla Vogel
    Citation: Particle and Fibre Toxicology 2019 16:44

    The original article was published in Particle and Fibre Toxicology 2019 16:11

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