Evaluation of cytotoxic, genotoxic and inflammatory responses of nanoparticles from photocopiers in three human cell lines

Table 1 Magnetic sector inductively coupled plasma mass spectrometry (SF-ICP-MS) analysis of the nanoscale fraction collected with the Harvard Compact Cascade Impactor (CCI)

Element	Fe	Ti	Si ^a	Mn	Al	Zn	S	Cu	Cr	Ni	Mo	Mg	Ca	P
Total
(SD)	4393	5671	5711	99.3	1371	2312	59087	286.3	39.7	101.1	38.4	679.0	2609	559.6
(μg/g)	(219)	(254)	(2690)	(5.8)	(69.4)	(122)	(2803)	(17.1)	(2.6)	(5.6)	(1.73)	(36.9)	(254)	(45.6)
Water soluble
(SD)	395.4	0.78	n/a	48.81	111.1	2263	60196	128.5	8.12	51.21	21.84	395.4	2421	553.3
(μg/g)	(11.7)	(0.53)	n/a	(1.48)	(2.7)	(28.1)	(262)	(2.54)	(0.32)	(2.92)	(0.16)	(11.73)	(104.71)	(61.8)
% Water soluble	9	93	n/a	49	8.1	98	101	45	20	51	57	58	93	99

Elemental analysis targeted 47 elements,of which the following were the most abundant. Other elements of toxicological relevance (V, Co, As, Cd, Pb) were detected in trace amounts. The remainder elements tested for were: Li, B, K, Sc, Rb, Sr, Y, Nb, Rh, Pd, Ag, Sn, Sb, Cs, Ba, La, Ce, Pr, Nd, Sm, Eu, Dy, Ho, Yb, Lu, Pt, Th, U. Values are rounded to the nearest integer.
^a Silicon is an estimate based on reanalysis of initial digests and it is likely to be underestimated in some fractions. Values have been corrected for recovery.
n/a, not analyzed.

ISSN: 1743-8977