Figure 2
From: Lung tumor promotion by chromium-containing welding particulate matter in a mouse model
Lung tumor multiplicity (left panel) and total lung tumor number (right panel) upon gross examination in A/J mice promoted with PBS (sham) or GMA-SS welding PM. At 30 weeks, MCA initiation followed by GMA-SS exposure increased lung tumor multiplicity (average number of tumors/mouse ± SE) in both the low dose (12.1 ± 1.5) and high dose (14.0 ± 1.8) groups significantly above that of MCA/sham (4.77 ± 0.7). **p < 0.0001; *p < 0.0001- compared to corn oil/sham. Right panel shows increased total lung tumor numbers in the MCA/GMA-SS low and high dose groups above that of the MCA/sham.