Figure 4
From: Lung tumor promotion by chromium-containing welding particulate matter in a mouse model
Lung tumor/proliferation multiplicity (left panel) and total number (right panel) microscopically observed in A/J mice promoted with PBS (sham) or GMA-SS welding PM. At 30 weeks, MCA initiation followed by GMA-SS exposure increased multiplicity (average number of tumors and proliferations/mouse ± SE) in both the low dose (5.85 ± 0.76) and high dose (6.00 ± 0.87) groups significantly above that of MCA/sham (2.15 ± 0.32). **p < 0.0001; *p < 0.0001- compared to corn oil/sham. Right panel shows increased total lung lesion numbers in the MCA/GMA-SS low and high dose groups above that of the MCA/sham.