Lung tumor promotion by chromium-containing welding particulate matter in a mouse model

Table 1 Total tumor number across individual lung lobes in A/J mice following exposure to GMA-SS welding PM at 30 weeks post-initiation with MCA or corn oil

	n	Left	Apical	Cardiac	Diaphragmatic	Azygos
Corn oil/Sham	28	1	1	2	2	0
Corn oil/GMA-SS low	26	4	3	2	1	1
Corn oil/GMA-SS high	28	4	1	0	1	0
MCA/Sham	26	52^*	12^*	13^*	39^*	8^*
MCA/GMA-SS low	26	119^**	46^**	40^#	81^#	28^#
MCA/GMA-SS high	29	132^**	64^**	66^**	106^**	37^#

GMA-SS gas metal arc-stainless steel, PM particulate matter, MCA 3-methylcholanthrene.
^* p < 0.002 - compared to corn oil/sham.
^** p < 0.0007, ^# p < 0.004 - compared to MCA/sham.

ISSN: 1743-8977