Figure 1

Effects of diesel exhaust exposure and angiotensin II on cardiac hypertrophy. Angiotensin II was infused (800 ng/kg/min) via osmotic minipump in conjunction with either DE (300 μg/m³, non-ozone treated) or FA exposure for 4 weeks (6 hr/day, 5 days/week). A. Ventricular weight to body weight ratio (VW/BW). N = 8 for all groups. B. Left ventricular wall thickness (LV WT). N = 10 for all groups. C. Left ventricular end diastolic dimension (LVEDD). N = 10 for all groups. D. Left ventricular ejection fraction (LVEF). N = 10 for all groups. FA: filtered air. DE: diesel exhaust.