Figure 7
From: Exaggerated effects of particulate matter air pollution in genetic type II diabetes mellitus
Effect of PM 2.5 exposure on BAT-specific gene profiles and UCP1 expression in KKay mice. (A), Altered protein levels of UCP1 in interscapular BAT in response to PM2.5 exposure. (B), Altered mRNA levels of BAT-specific gene profiles in BAT in response to PM2.5 exposure. (C), Expression of inflammation-related genes in BAT in response to PM2.5 exposure. *P < 0.05 compared to respective FA group. n = 6-8 per group. uncoupling protein 1 (UCP1), peroxisome proliferator-activated receptor-γ coactivator 1-α (PGC-1 α), PRD1-BF1-RIZ1 homologous domain containing 16 (PRDM 16), elongation of very long chain fatty acid 3 (ELOV3), Cell death-inducing DNA fragmentation factor--like effector A (Cidea), Carnitine palmitoyltransferase 1 muscle isoform (CPT-1 M).