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Figure 6 | Particle and Fibre Toxicology

Figure 6

From: Inflammasome activation in airway epithelial cells after multi-walled carbon nanotube exposure mediates a profibrotic response in lung fibroblasts

Figure 6

Role of NLRP3 inflammasome activation in HBE cells in inducing a pro- fibrotic gene expression in fibroblasts. A- E) Modulation of TIMP-1, TN-C, PC-1, OPN and TGF-β using conditioned media from HBE cells transfected with siRNA against NLRP-3 inflammasome. Data were analyzed by analysis of variance (ANOVA) followed by Tukey’s post hoc test. Graphs show average ± SEM of three independent experiments with triplicate of each conditions, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 (between media-treated control and treatment).

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Particle and Fibre Toxicology

ISSN: 1743-8977

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