Table 3 Resting variables for all arterioles studied in intravital studies.
From: Nanoparticle inhalation augments particle-dependent systemic microvascular dysfunction
| Â | Exposure Parameters | Â | Â | Â | Â | |
|---|---|---|---|---|---|---|
TiO 2 Dose/Group | Aerosol Concentration (mg/m 3 ) | Duration (min) | n | Resting Diameter (μm) | Passive Diameter (μm) | Resting Tone (% of maximum) |
Sham Control | 0 | 240 | 8 | 40 ± 2 | 99 ± 4 | 59 ± 3 |
38 μg Ultrafine | 10 | 720 | 9 | 42 ± 2 | 106 ± 5 | 60 ± 3 |
19 μg Ultrafine | 12 | 240 | 11 | 42 ± 1 | 100 ± 5 | 57 ± 3 |
10 μg Ultrafine | 6 | 240 | 8 | 40 ± 2 | 98 ± 2 | 59 ± 3 |
10 μg Ultrafine | 3 | 480 | 10 | 40 ± 2 | 95 ± 4 | 57 ± 3 |
10 μg Ultrafine | 12 | 120 | 10 | 45 ± 2 | 99 ± 7 | 54 ± 3 |
6 μg Ultrafine | 3 | 240 | 7 | 39 ± 1 | 105 ± 5 | 62 ± 2 |
4 μg Ultrafine | 1.5 | 240 | 9 | 38 ± 1 | 97 ± 4 | 60 ± 2 |
90 μg Fine | 15 | 480 | 8 | 45 ± 1 | 106 ± 5 | 57 ± 3 |
67 μg Fine | 16 | 300 | 8 | 41 ± 1 | 105 ± 2 | 61 ± 2 |
36 μg Fine | 12 | 240 | 8 | 39 ± 2 | 100 ± 7 | 60 ± 3 |
20 μg Fine | 6 | 240 | 7 | 39 ± 1 | 92 ± 2 | 57 ± 2 |
8 μg Fine | 3 | 240 | 12 | 41 ± 1 | 100 ± 5 | 58 ± 2 |