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Table 3 Gross lung tumor findings for A/J mice 48 and 78 weeks post-exposure

From: Pulmonary inflammation and tumor induction in lung tumor susceptible A/J and resistant C57BL/6J mice exposed to welding fume

Exposure

Lung Tumor Multiplicity*

Lung Tumor Incidence†

 

48 wk

78 wk

48 wk

78 wk

Sham

0.38 ± 0.13 (21)

1.00 ± 0.35 (19)

33% (7/21)

53% (10/19)

GMA-MS

Gas metal arc-mild steel

0.42 ± 0.14 (24)

1.00 ± 0.22 (20)

33% (8/24)

65% (13/20)

GMA-SS

Gas metal arc-stainless steel

0.45 ± 0.14 (20)

1.75 ± 0.32 (16)

40% (8/20)

81% (13/16)

MMA-SS

Manual metal arc-stainless steel

0.25 ± 0.11 (24)

1.55 ± 0.34 (20)

21% (5/24)

80% (16/20)

  1. *Average number of tumors per lung (± SE) and includes mice with no tumors. Parentheses indicate total animal number. †Percentage of tumor-bearing mice out of the total. Parentheses indicate tumor-bearing/total animal number.