Skip to main content

Table 3 The predictive value of the estimates (% change) with 95% confidence intervals relative to exposure to non-filtered air in mixed effects models.

From: Exposure to ambient concentrations of particulate air pollution does not influence vascular function or inflammatory pathways in young healthy individuals

Outcome variables

% change (CI)

Microvascular function scoreb

1.11 (-3.92, 7.25)

Haemoglobin (mmol/L)

-0.30 (-1.00, 1.01)

Red blood cells (×1012/L)

-0.20 (-1.00, 1.00)

Fibrinogen (μmol/L)

-1.10 (-2.96, 1.01)

Platelets (×109/L)

-0.20 (-1.98, .02)

Coagulation factor (II+VII+X)

-1.29 (-1.98, 1.01)

C-reactive protein (mg/L)

-9.97 (-19.7, 1.01)

Interleukin-6 (ng/L)

-0.20 (-12.2, 13.9)

Tumour necrosis factor-α (ng/L)

-1.98 (-7.69,4.08)

PLAAS (pmol/mg protein)c

-2.08 (-7.69, 3.05)

AAPH(lagtime min)d

1.82 (-1.00, 4.08)

  1. aMixed model regression with subject nested in gender used as random factor and the natural logarithm of the biomarker in question included as a continuous outcome variable. All models adjusted for age, BMI, activity and time of sampling. Non-filtered air was included in the models as a categorical (yes/no) fixed effects predictor variable. Mutual adjustment with gases did not have significant effect on the significance of the main exposure variable (not shown)
  2. bA detailed description of the microvascular function score and its relation to endothelial function is provided in the methods section
  3. c2-aminoapidic semialdehyde in plasma proteins
  4. dSusceptibility to lipoprotein oxidation in plasma was measured as lagtime (min) of ex vivo oxidation with AAPH (2,2'-azobis(2-aminopropane)dihydrochloride)
Back to article page

Particle and Fibre Toxicology

ISSN: 1743-8977

Contact us