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Table 4 Effects of particulate pollutants on fibrinogen, E-selectin, and vWF presented as % change from the arithmetic mean in the blood marker (linear regression) per increase in IQR air pollutant; 38 men with chronic pulmonary disease in Erfurt, Germany, between October 2001 and May 2002

From: Short-term effects of air pollution: a panel study of blood markers in patients with chronic pulmonary disease

Polutant

Fibrinogen

E-Selectin

vWF††

 

%change AM ††

95%CI

%change AM††

95%CI

%change AM ††

95%CI

UFP

      

Lag0#

0.5

-1.8 ; 2.9

-1.2

-3.9 ; 1.4

0.1

-2.7 ; 2.9

Lag1#

2.5 *

0.2 ; 4.9

0.2

-2.7 ; 3.1

-0.4

-3.3 ; 2.5

Lag2#

-1.6

-4.3 ; 1.0

-2.0

-5.1 ; 1.0

-4.1 **

-7.3 ; -1.0

Lag3#

3.3 **

1.0 ; 5.6

-1.1

-4.3 ; 2.0

-4.3 **

-6.9 ; -1.6

Lag4#

1.5

-0.5 ; 3.5

1.6

-1.1 ; 4.2

-4.0 **

-6.4 ; -1.6

5-day-mean#

3.1 *

0.2 ; 6.0

-0.9

-4.5 ; 2.7

-6.1 ***

-9.7 ; -2.6

ACP

      

Lag0#

0.2

-3.7 ; 4.1

3.1 *

0.2 ; 6.1

2.6

-2.6 ; 7.7

Lag1#

0.5

-2.7 ; 3.7

4.0 **

1.1 ; 6.9

-2.3

-6.4 ; 1.7

Lag2#

-1.0

-3.9 ; 1.8

2.9 **

0.4 ; 5.3

-4.9 **

-8.1 ; -1.6

Lag3#

1.3

-1.1 ; 3.7

1.3

-1.0 ; 3.6

-4.2 **

-7.2 ; -1.2

Lag4#

0.8

-1.7 ; 3.3

2.1

0.0 ; 4.2

-6.3 ***

-9.7 ; -2.8

5-day-mean#

0.5

-3.6 ; 4.6

5.4 **

1.7 ; 9.1

-6.8 *

-12.2 ; -1.5

PM10

      

Lag0#

0.5

-1.7 ; 2.7

-1.1

-3.8 ; 1.6

2.1

-0.8 ; 5.0

Lag1#

0.1

-1.8 ; 2.0

2.6 *

0.2 ; 5.1

-1.6

-3.9 ; 0.7

Lag2#

-0.5

-2.3 ; 1.3

1.1

-1.1 ; 3.4

-2.2 *

-4.3 ; -0.1

Lag3#

2.4 **

0.6 ; 4.1

-0.1

-2.5 ; 2.3

-2.4 *

-4.7 ; -0.2

Lag4#

1.8 *

0.1 ; 3.5

0.3

-2.0 ; 2.6

-1.9

-4.2 ; 0.5

5-day-mean#

1.9

-0.5 ; 4.3

1.4

-1.9 ; 4.7

-3.3 *

-6.6 ; -0.1

OC

      

Lag0#

0.1

-2.6 ; 2.7

-1.0

-4.1 ; 2.1

-1.1

-4.7 ; 2.4

Lag1#

0.1

-1.9 ; 2.1

2.7 *

0.2 ; 5.1

-3.3 **

-5.7 ; -0.9

Lag2#

0.1

-1.7 ; 1.9

0.6

-1.6 ; 2.9

-4.6 ***

-6.7 ; -2.4

Lag3#

2.1 *

0.5 ; 3.6

0.1

-2.1 ; 2.2

-4.7 ***

-6.9 ; -2.6

Lag4#

1.5

-0.1 ; 3.1

0.6

-1.5 ; 2.7

-4.5 ***

-7.0 ; -2.0

5-day-mean#

1.4

-0.5 ; 3.2

0.9

-1.5 ; 3.4

-6.4 ***

-9.1 ; -3.6

EC

      

Lag0#

0.5

-1.9 ; 2.9

-2.1

-4.9 ; 0.7

-0.5

-3.6 ; 2.7

Lag1#

0.2

-1.7 ; 2.1

2.5 *

0.2 ; 4.7

-2.7 *

-4.9 ; -0.4

Lag2#

-0.5

-2.2 ; 1.3

0.8

-1.3 ; 2.9

-4.0 ***

-6.1 ; -1.9

Lag3#

2.5 **

0.9 ; 4.0

-0.2

-2.3 ; 1.9

-3.6 ***

-5.5 ; -1.7

Lag4#

1.8 *

0.3 ; 3.2

0.7

-1.2 ; 2.6

-3.3 ***

-5.4 ; -1.2

5-day-mean#

2.0

-0.1 ; 4.1

0.9

-1.9 ; 3.7

-6.4 ***

-9.4 ; -3.4

  1. IQR, interquartile range; ††AM: arithmetic mean; %-change: effect estimate obtained from regression divided by arithmetic mean of fibrinogen
  2. vWF, von Willebrand factor antigen § UFP, ultrafine particles number concentration of particles with a size range of 0.01 to 0.1 μm in diameter; ACP, accumulation mode particles, particles with a size range of 0.1 to 1.0 μm; PM10, mass concentration of particles less than 10 μm in diameter; OC, organic carbon; EC, elemental carbon
  3. # lag 0 (lag 1/lag 2/lag 3/lag 4/5-day-mean) = average pollutant concentration 0-23 (24-47/48-71/72-95/96-119/0-119) hours prior to blood withdrawal
  4. * p < 0.05; ** p < 0.01; *** p < 0.001; p ≤ 0.1