P values for comparison of changes between filtered air and diesel exhaust | |||||||
---|---|---|---|---|---|---|---|
Pre-exposed | 2 hr | 6 hr | Δ 2 hr | Δ 6 hr | Δ 2 hr | Δ 6 hr | |
Filtered air (n = 16) | |||||||
Ks (×10 -9 cm 2 ) | 5.17 ± 1.48 | 5.27 ± 2.64 | 5.13 ± 1.22 | 0.10 ± 2.01 | -0.04 ± 0.92 | - | - |
ODmax | 0.230 ± 0.051 | 0.255 ± 0.078 | 0.233 ± 0.059 | 0.025 ± 0.042 | 0.003 ± 0.021 | - | - |
Lag time (seconds) | 917 ± 321 | 906 ± 352 | 922 ± 482 | -11 ± 302 | 5 ± 385 | - | - |
Fibre Diameter (nm) | 458 ± 18 | 457 ± 18 | 470 ± 25 | -1 ± 18 | 12 ± 24 | - | - |
Fibre Density (fibres/120 μm) | 7.3 ± 1.6 | 7.5 ± 1.6 | 7.2 ± 1.8 | 0.2 ± 1.1 | -0.1 ± 2.1 | - | - |
Fibrinogen level (mg/ml) | 2.05 ± 0.43 | 2.12 ± 0.43 | 1.81 ± 0.31 | 0.07 ± 0.48 | -0.24 ± 0.36 | - | - |
Diesel Exhaust (n = 15) | |||||||
Ks (× 10 -9 cm 2 ) | 4.94 ± 1.89 | 5.44 ± 1.46 | 4.85 ± 1.26 | 0.51 ± 1.95 | -0.09 ± 1.32 | 0.55 | 0.90 |
ODmax | 0.246 ± 0.044 | 0.244 ± 0.039 | 0.238 ± 0.039 | -0.002 ± 0.024 | -0.008 ± 0.036 | 0.03§ | 0.17 |
Lag time (seconds) | 846 ± 223 | 788 ± 226 | 737 ± 201 | -58 ± 270 | -109 ± 226 | 0.64 | 0.56 |
Fibre Diameter (nm) | 455 ± 21 | 459 ± 16 | 465 ± 21 | 4 ± 21.7 | 10 ± 24.4 | 0.54 | 0.91 |
Fibre Density (fibres/120 μm) | 7.8 ± 1.4 | 8.1 ± 1.7 | 8.1 ± 1.7 | 0.3 ± 1.2 | 0.3 ± 1.2 | 0.97 | 0.59 |
Fibrinogen level (mg/ml) | 2.10 ± 0.45 | 2.08 ± 0.41 | 1.96 ± 0.22 | -0.02 ± 0.33 | -0.14 ± 0.32 | 0.76 | 0.26 |