Multi-walled carbon nanotube instillation impairs pulmonary function in C57BL/6 mice

Table 1 Effect of MWCNT instillation on pulmonary cell populations in C57BL/6 mice

Treatment	Macrophages (×10³)	Epithelial Cells (×10³)	Neutrophils (×10³)	Eosinophils (×10³)	Lymphocytes (×10³)	Total Cells (×10³)
Vehicle	113.71 ± 11.51	22.60 ± 3.80	0.18 ± 0.09	0.25 ± 0.14	0.05 ± 0.05	136.77 ± 11.68
1 mg/kg MWCNT	247.4 ± 20.77	22.0 ± 5.39^Ŧ	0.50 ± 0.25^Ŧ	0.66 ± 0.35	2.55 ± 1.90	273.17 ± 21.58
2 mg/kg MWCNT	230.75 ± 52.41	18.85 ± 1.78^Ŧ	2.35 ± 1.24^Ŧ	1.55 ± 1.03	0.10 ± 0.10	253.60 ± 54.36.
4 mg/kg MWCNT	331.62 ± 61.92**	59. 54 ± 6.34**	16.17 ± 3.90**	2.87 ± 1.67	1.24 ± 0.67	441.28 ± 68.13**

Values are mean ± SEM. N = 6/group; *p < 0.01 vs vehicle; **p < 0.001 vs vehicle, ^Ŧ p < 0.05 vs 4 mg/kg MWCNT

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