Figure 5

Exposure to CAPs, Ni, or CAPs+Ni induces microvascular dysfunction . A. Representative images of adherent leukocytes in the cremasteric microcirculation (cells with arrow heads indicate adherent monocytes, cells without arrow heads indicate rolling leukocytes) by intravital microscopy. Scale bar, 50 μm. B and C, Statistical analysis of monocyte rolling flux (B) and adhesion (C) in cremasteric microcirculation. N = 5–6. ^* P < 0.05 vs. FA; ^** P < 0.001 vs. FA; ^# P < 0.05 vs. CAPs; ^## P < 0.001 vs. CAPs; ^{^} P < 0.05 vs. Ni group.