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Figure 3 | Particle and Fibre Toxicology

Figure 3

From: Carbon nanoparticles induce ceramide- and lipid raft-dependent signalling in lung epithelial cells: a target for a preventive strategy against environmentally-induced lung inflammation

Figure 3

Ceramide-dependent signalling steps are associated with lung inflammation in mice. Activation of signalling steps in lung homogenate and induction of inflammation determined in BAL in mice (n = 5) treated with PBS, CNP [5 mg/kg bodyweight], or CNP together with ectoine [E, 1 mM]. (A) Phospho-EGFR at Tyr1173 signals relative to total EGFR signals. (B) Phospho-SFK at Tyr416 signals relative to GAPDH signals. (C) Neutrophilic granulocytes in BAL (D) KC in BAL. *, Significantly different from control; †, significantly different from CNP alone (p < 0.05).

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Particle and Fibre Toxicology

ISSN: 1743-8977

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