Fig. 2From: Direct stimulation of human fibroblasts by nCeO2 in vitro is attenuated with an amorphous silica coatingnCeO2 directly induces proliferation of NHLFs, while amsCeO2 does not. Quantitation of DAPI stained nuclei of NHLFs that had been treated for 48 h was used to determine cell counts at the indicated doses and treatments. nCeO2 induced a significant increase in cell proliferation at both 0.006 μg/cm2 (a) and 0.2 μg/cm2 (b) compared to non-treated cells as well as those treated with amsCeO2. SWCNTs and TGFβ (1 ng/mL) were used as positive controls and also significantly increased proliferation of the fibroblast cells. Statistical significance is indicated as *p < 0.05, **p < 0.01, and ***p < 0.001 compared to non-treated (NT) conditions and #p < 0.05 and ##p < 0.01 for nCeO2 compared to amsCeO2 Back to article page