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Table 3 Overall Effects of P + SOA exposure on ND and MetS rats

From: Inhaled ambient-level traffic-derived particulates decrease cardiac vagal influence and baroreflexes and increase arrhythmia in a rat model of metabolic syndrome

  

ND

MetS

MetS vs. ND

effect

P

effect

P

P

 

Diastolic Pressure (mmHg)

-0.45

0.874

−0.532

0.830

0.1073

 

Systolic Pressure (mmHg)

2.97*

0.044

−1.26

0.692

0.021*

 

Aortic dP/dt max (mmHg/ms)

157*

0.013

−109*

0.007

<0.001*

 

Pulse Pressure (mmHg)

3.26*

0.020

−1.97*

0.035

<0.001*

 

Rate × Pressure (BPM*mmHg/1000)

0.098

0.927

−0.860

0.654

0.05*

 

Heart Rate (BPM)

4.70

0.660

−1.74

0.814

0.458

 

BRS (ms/mmHg)

0.167

0.807

−0.338

0.095

0.009*

HRV

RMSSD (ms)

−0.023

0.946

−1.31*

0.027

0.076

 

SDNN (ms)

−0.101

0.855

−0.245

0.729

0.913

 

HF (ms2)

  

−0.921

0.068

 
 

LF (ms2)

  

0.116

0.630

 

ECG

PR Interval (ms)

  

−1.27*

0.036

 
 

QTc Interval (ms)

  

−2.16*

0.025

 
  1. Overall differences between diet-matched P + SOA- and FA-exposed groups in cardiovascular physiologic deltas from baseline or between opposing diets with exposure to P + SOA (right column, significance only). *indicates P < 0.05 by linear mixed model analysis
  2. The italic font indicated significant differences
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Particle and Fibre Toxicology

ISSN: 1743-8977

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