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Fig. 8 | Particle and Fibre Toxicology

Fig. 8

From: Mechanistic understanding of nanoparticles’ interactions with extracellular matrix: the cell and immune system

Fig. 8

Drug-loaded G5-N-Acetylgalactosamine (NAcGal) conjugate that can bind to the asialoglycoprotein receptor (ASGPR) expressed on the surface of hepatic cancer cells. Binding of the drug-loaded conjugate to ASGPR triggers receptor-mediated endocytosis followed by endosomal escape and release of the drug, ASPGR recycles to be again expressed on the cell’s surface

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