Fig. 6
From: Chronic effects of two rutile TiO2 nanomaterials in human intestinal and hepatic cell lines
Effects of repeated treatment with TiO2 NMs on IL-8 secretion in differentiated Caco-2 and HepaRG cells. Caco-2 cells (A, B) and HepaRG cells (C, D) were treated with concentrations of NM-103 (A, C) and NM-104 (B, D) ranging from 0.313 to 80 ug/cm2 for 24 h (light blue), 24 h with a 24 h recovery period (blue), 1 week (light green), 1 week with a 1-week recovery period (green) or 2 weeks (grey). Cell culture media were collected and analyzed at the end of the treatment period. Data are presented as the mean ± SEM from three (Caco-2) or four (HepaRG) independent experiments