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Fig. 3 | Particle and Fibre Toxicology

Fig. 3

From: Chronic maternal exposure to titanium dioxide nanoparticles alters breathing in newborn offspring

Fig. 3

The number and duration of apneas are significantly lower in prenatally-exposed offspring. A Schematic of experimental procedure. B Whole-body plethysmographic recordings of non-exposed (top green) and TiO2 NP-exposed (bottom purple) neonates obtained at P1. C, E Bar charts showing the variation in the number (C) and duration (E) of apneas in non-exposed (green bars) and prenatally TiO2 NP (200 µg/g)-exposed (purple bars) groups during the first postnatal week (mean ± SEM). D, F Bar charts illustrating the dose-dependent effect of a gestational exposure to TiO2 NPs on the number (D) and duration (F) of apneas under the four experimental conditions. Data were pooled from P0 to P6. The number of animals is indicated in each bar. *p < 0.05; **p < 0.01; ***p < 0.001

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