Fig. 2From: Amine-modified nanoplastics promote the procoagulant activation of isolated human red blood cells and thrombus formation in ratsUptake and morphological changes in human RBCs by PS-NPs. We confirmed the uptake of PS-NPs in RBCs using confocal microscopy (n = 4) (A) and flow cytometry (n = 4) (B). Changes in the shape of RBCs by PS-NPs were observed using TEM (n = 4) (C) and SEM (n = 4) (D). The yellow arrows indicate spiny RBCs, called echinocytes, and spherocytes. Aggregation occurs by PS-NPs indicated by the red arrows. The black arrows show PS-NPs attached to the surface of RBCs. Data are presented as the mean ± SE. ***p < 0.001 versus control (CON)Back to article page