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Fig. 8 | Particle and Fibre Toxicology

Fig. 8

From: Derivation of first-order dissolution rates to estimate particle clearance and burden in the human respiratory tract

Fig. 8

Total dissolution (all lung regions and the gastrointestinal tract) of particles normalized to deposition of material in the respiratory tract. Monodisperse aerosol (concentration = 1.0 µg/m3) of indicated sized particles (density = 3 g/cm3) were inhaled for 8-h/day for 3 years by adult male exposed while sitting at rest. The daily dissolution reflects that occurring on day 1095 of exposure with gastrointestinal absorption of 10%

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