Test article | Total dose | Male | Female | ||||||
---|---|---|---|---|---|---|---|---|---|
(mg/kg) | (fibers/animal) | (fibers/animal) | |||||||
Week 13 | Week 104 | Week 13 | Week 104 | ||||||
Control | 0 | – | – | – | – | ||||
MWNT-7 | 0.128 | 1421 ± 772 | (5) | 4070 ± 2226 | (5) | 1445 ± 493 | (5) | 1338 ± 924 | (5) |
MWNT-7 | 0.64 | 4994 ± 3107 | (5) | 9134 ± 9059 | (5) | 4011 ± 2416 | (5) | 16,938 ± 14,546 | (5) |
MWNT-7 | 3.2 | 51,134 ± 17,273 | (5) | 6520 | (1) | 8835 ± 4166 | (5) | 8174 ± 3419 | (4) |
VGCF™-H | 0.128 | 77 ± 70 | (5) | 144 ± 128 | (5) | 48 ± 66 | (5) | 99 ± 106 | (5) |
VGCF™-H | 0.64 | 339 ± 239 | (5) | 1090 ± 549 | (5) | 93 ± 97 | (5) | 312 ± 253 | (5) |
VGCF™-H | 3.2 | 1332 ± 224 | (5) | 5270 ± 2325 | (5) | 78 ± 72 | (5) | 2285 ± 1843 | (5) |