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Table 5 Particle penetration (50% cut-point) through respiratory tract regions relative to particles entering the respiratory tract

From: Thoracic and respirable particle definitions for human health risk assessment

V daily(%-tile)

Normal

 

Gradual

 
 

Augmenter

Mouth-breather

Augmenter

Oral only

 

P(ET) avg

P(TB) avg

P(ET) avg

P(TB) avg

P(ET) avg

P(TB) avg

P(ET) avg

P(TB) avg

Male

        

5%

2.94 a

2.74

5.15

4.32

3.60

3.25

9.00

6.67

95% CI

(1.72–5.03)

(1.65–4.34)

(3.12–8.48)

(2.84–6.10)

(2.11–6.11)

(2.00–4.98)

(5.86–13.8)

(5.00–8.14)

50%

2.46

2.30

5.09

4.30

3.37

3.05

8.09

6.11

95% CI

(1.44–4.20)

(1.38–3.71)

(3.14–8.26)

(2.86–5.88)

(1.99–5.67)

(1.88–4.65)

(5.26–12.4)

(4.58–7.34)

95%

2.14

2.03

5.08

4.31

3.19

2.90

7.61

5.89

95% CI

(1.25–3.66)

(1.20–3.32)

(3.16–8.16)

(2.89–5.83)

(1.90–5.33)

(1.79–4.44)

(4.95–11.7)

(4.38–7.07)

Female

        

5%

2.92

2.71

4.32

3.78

3.10

2.86

8.78

6.50

95% CI

(1.71–5.01)

(1.63–4.28)

(2.57–7.22)

(2.40–5.52)

(1.81–5.30)

(1.73–4.48)

(5.71–13.5)

(4.88–7.91)

50%

2.42

2.27

4.46

3.87

2.91

2.68

7.88

5.96

95% CI

(1.41–4.13)

(1.36–3.64)

(2.72–7.32)

(2.51–5.45)

(1.71–4.94)

(1.63–4.19)

(5.13–12.1)

(4.47–7.17)

95%

2.10

1.99

4.58

3.96

2.74

2.54

7.44

5.77

95% CI

(1.23–3.60)

(1.18–3.26)

(2.82–7.42)

(2.60–5.49)

(1.61–4.64)

(1.53–4.00)

(4.84–11.4)

(4.29–6.94)

Child-B b

        

5%

2.77

2.61

4.31

3.78

4.30

3.78

8.34

6.46

95% CI

(1.62–4.75)

(1.56–4.18)

(2.58–7.19)

(2.40–5.57)

(2.57–7.17)

(2.40–5.56)

(5.42–12.8)

(4.74–8.04)

50%

2.25

2.13

4.37

3.81

4.07

3.59

7.50

5.81

95% CI

(1.31–3.85)

(1.27–3.48)

(2.67–7.15)

(2.47–5.35)

(2.46–6.71)

(2.29–5.15)

(4.88–11.5)

(4.32–7.08)

95%

1.89

1.81

4.34

3.76

3.98

3.49

6.91

5.33

95% CI

(1.11–3.24)

(1.07–2.98)

(2.69–7.03)

(2.48–5.11)

(2.45–6.47)

(2.27–4.88)

(4.49–10.6)

(4.01–6.36)

Child-A c

        

5%

3.92

3.56

5.60

4.72

5.59

4.72

8.34

6.46

95% CI

(2.29–6.72)

(2.18–5.44)

(3.38–9.28)

(3.09–6.63)

(3.37–9.27)

(3.09–6.62)

(5.42–12.8)

(4.74–8.04)

50%

3.18

2.94

5.37

4.53

5.12

4.36

7.50

5.81

95% CI

(1.86–5.45)

(1.77–4.58)

(3.29–8.77)

(3.03–6.10)

(3.11–8.40)

(2.88–5.95)

(4.88–11.5)

(4.32–7.08)

95%

2.68

2.50

5.16

4.34

4.85

4.14

6.91

5.33

95% CI

(1.56–4.58)

(1.50–3.97)

(3.19–8.34)

(2.94–5.66)

(2.98–7.90)

(2.76–5.51)

(4.49–10.6)

(4.01–6.36)

  1. P(ET)avg, extrathoracic particle penetration which is the thoracic particle fraction averaged across all activity levels weighted by daily ventilation; P(TB)avg, tracheobronchial particle penetration which is the respirable particle fraction averaged across all activity levels weighted by daily ventilation; 95% CI, ninety-five percent confidence intervals for inter-individual variability attributable to differences in particle penetration through the extrathoracic region; a Aerodynamic particle diameter in μm; b Scaling factor in Equations 2 and 3 equal to 1.26; c Scaling factor in Equations 2 and 3 equal to 1.0.