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  1. With the large-scale production and application of amorphous silica nanoparticles (aSiNPs), its adverse health effects are more worthy of our attention. Our previous research has demonstrated for the first tim...

    Authors: Liyan Xiao, Jinyan Pang, Hua Qin, Liyang Dou, Man Yang, Ji Wang, Xianqing Zhou, Yang Li, Junchao Duan and Zhiwei Sun
    Citation: Particle and Fibre Toxicology 2023 20:34
  2. Nanodiamonds (NDs) have gained a rapidly growing interest in biomedical applications; however, little is known regarding their biokinetics owing to difficulties in measurements and limited synthesis/purificati...

    Authors: Jiyoung Jeong, Soyeon Jeon, Songyeon Kim, Sinuk Lee, Gyuri Kim, Eunsol Bae, Yeonjeong Ha, Seung Whan Lee, Ji-Su Kim, Dong-Jae Kim and Wan-Seob Cho
    Citation: Particle and Fibre Toxicology 2023 20:33
  3. Pulmonary exposure to multi-walled carbon nanotubes (MWCNTs) has been reported to exert strong pro-inflammatory and pro-fibrotic adjuvant effects in mouse models of allergic lung disease. However, the molecula...

    Authors: Ho Young Lee, Dorothy J. You, Alexia Taylor-Just, Logan J. Tisch, Ryan D. Bartone, Hannah M. Atkins, Lauren M. Ralph, Silvio Antoniak and James C. Bonner
    Citation: Particle and Fibre Toxicology 2023 20:32
  4. Traffic-derived particles are important contributors to the adverse health effects of ambient particulate matter (PM). In Nordic countries, mineral particles from road pavement and diesel exhaust particles (DE...

    Authors: Magne Refsnes, Tonje Skuland, Rikke Jørgensen, Vegard Sæter-Grytting, Brynhild Snilsberg, Johan Øvrevik, Jørn A. Holme and Marit Låg
    Citation: Particle and Fibre Toxicology 2023 20:31
  5. Exposure to wood smoke has been shown to contribute to adverse respiratory health effects including airway infections, but the underlying mechanisms are unclear. A preceding study failed to confirm any acute i...

    Authors: Alva Hansson, Gregory Rankin, Oskari Uski, Maria Friberg, Jamshid Pourazar, Robert Lindgren, Natxo García-López, Christoffer Boman, Thomas Sandström, Annelie Behndig and Ala Muala
    Citation: Particle and Fibre Toxicology 2023 20:30
  6. Chronic exposure to silica can lead to silicosis, one of the most serious occupational lung diseases worldwide, for which there is a lack of effective therapeutic drugs and tools. Epithelial mesenchymal transi...

    Authors: Shaoqi Yang, Yuheng Sun, Min Long, Xinbei Zhou, Mengqin Yuan, Liliang Yang, Wei Luo, Yusi Cheng, Xinxin Zhang, Wei Jiang and Jie Chao
    Citation: Particle and Fibre Toxicology 2023 20:29
  7. Exposure to particulate matter (PM) with an aerodynamic diameter less than 2.5 μm (PM2.5) is a risk factor for developing pulmonary diseases and the worsening of ongoing disease. Mitochondrial fission and fusion ...

    Authors: Qi Liu, Jiali Weng, Chenfei Li, Yi Feng, Meiqin Xie, Xiaohui Wang, Qing Chang, Mengnan Li, Kian Fan Chung, Ian M Adcock, Yan Huang, Hai Zhang and Feng Li
    Citation: Particle and Fibre Toxicology 2023 20:28
  8. Edible gold (Au) is commonly used as a food additive (E175 in EU) for confectionery and cake decorations, coatings and in beverages. Food-grade gold is most often composed of thin Au sheets or flakes exhibitin...

    Authors: Lauris Evariste, Bruno Lamas, Sandrine Ellero-Simatos, Laure Khoury, Christel Cartier, Eric Gaultier, Benoit Chassaing, Nicolas Feltin, Laurent Devoille, Georges Favre, Marc Audebert and Eric Houdeau
    Citation: Particle and Fibre Toxicology 2023 20:27
  9. There is insufficient knowledge about the systemic health effects of exposure to fine (PM2.5) and ultrafine particles emitted from typical indoor sources, including cooking and candlelight burning. We examined wh...

    Authors: Karin Rosenkilde Laursen, Nichlas Vous Christensen, Frans AA Mulder, Jörg Schullehner, Hans Jürgen Hoffmann, Annie Jensen, Peter Møller, Steffen Loft, Anna-Carin Olin, Berit B. Rasmussen, Bernadette Rosati, Bo Strandberg, Marianne Glasius, Merete Bilde and Torben Sigsgaard
    Citation: Particle and Fibre Toxicology 2023 20:26
  10. We previously found that air pollution particles reaching the gastrointestinal tract elicit gut inflammation as shown by up-regulated gene expression of pro-inflammatory cytokines and monocyte/macrophage marke...

    Authors: Angela J. T. Bosch, Theresa V. Rohm, Shefaa AlAsfoor, Andy J. Y. Low, Zora Baumann, Neena Parayil, Faiza Noreen, Julien Roux, Daniel T. Meier and Claudia Cavelti-Weder
    Citation: Particle and Fibre Toxicology 2023 20:25
  11. Titanium dioxide (TiO2), no matter in nanoscale or micron sizes, has been widely used in food industry as additives for decades. Given the potential impact of TiO2 on the gastrointestinal epithelial and parenchym...

    Authors: Shumin Duan, Hongbo Wang, Yanjun Gao, Xiang Wang, Lizhi Lyu and Yun Wang
    Citation: Particle and Fibre Toxicology 2023 20:24
  12. Though titanium dioxide (TiO2) is generally considered to have a low impact in the human body, the safety of TiO2 containing nanosized particles (NPs) has attracted attention. We found that the toxicity of silver...

    Authors: Jun-ichi Akagi, Yasuko Mizuta, Hirotoshi Akane, Takeshi Toyoda and Kumiko Ogawa
    Citation: Particle and Fibre Toxicology 2023 20:23
  13. Copper oxide nanoparticles (Nano-CuO) are one of the most produced and used nanomaterials. Previous studies have shown that exposure to Nano-CuO caused acute lung injury, inflammation, and fibrosis. However, t...

    Authors: Yuanbao Zhang, Yiqun Mo, Yue Zhang, Jiali Yuan and Qunwei Zhang
    Citation: Particle and Fibre Toxicology 2023 20:22
  14. The widespread use of new engineered nanomaterials (ENMs) in industries such as cosmetics, electronics, and diagnostic nanodevices, has been revolutionizing our society. However, emerging studies suggest that ...

    Authors: João Meneses, Michael González-Durruthy, Eli Fernandez-de-Gortari, Alla P. Toropova, Andrey A. Toropov and Ernesto Alfaro-Moreno
    Citation: Particle and Fibre Toxicology 2023 20:21
  15. Airborne pollution particles have been shown to translocate from the mother’s lung to the fetal circulation, but their distribution and internal placental-fetal tissue load remain poorly explored. Here, we inv...

    Authors: Eva Bongaerts, Tim S Nawrot, Congrong Wang, Marcel Ameloot, Hannelore Bové, Maarten BJ Roeffaers, Pascale Chavatte-Palmer, Anne Couturier-Tarrade and Flemming R Cassee
    Citation: Particle and Fibre Toxicology 2023 20:20
  16. Asbestos is a fibrous mineral that was widely used in the past. However, asbestos inhalation is associated with an aggressive type of cancer known as malignant mesothelioma (MM). After inhalation, an iron-rich...

    Authors: Maya-Liliana Avramescu, Christian Potiszil, Tak Kunihiro, Kazunori Okabe and Eizo Nakamura
    Citation: Particle and Fibre Toxicology 2023 20:19
  17. Prussian blue (PB) nanoparticles (NPs) have been intensively investigated for medical applications, but an in-depth toxicological investigation of PB NPs has not been implemented. In the present study, a compr...

    Authors: Haijing Qu, Xing Jin, Wei Cheng, Dongqi Wu, Boyu Ma, Chenmei Lou, Jian Zheng, Lijia Jing, Xiangdong Xue and Yang Wang
    Citation: Particle and Fibre Toxicology 2023 20:18
  18. Inhalation is a portal-of-entry for aerosols via the respiratory tract where particulate burden accumulates depending on sites of particle deposition, normal clearance mechanisms, and particle solubility. The ...

    Authors: James S. Brown and Gary L. Diamond
    Citation: Particle and Fibre Toxicology 2023 20:17
  19. Exposure to micro- and nanoplastic particles (MNPs) in humans is being identified in both the indoor and outdoor environment. Detection of these materials in the air has made inhalation exposure to MNPs a majo...

    Authors: Chelsea M Cary, Talia N Seymore, Dilpreet Singh, Kinal N Vayas, Michael J Goedken, Samantha Adams, Marianne Polunas, Vasanthi R Sunil, Debra L Laskin, Philip Demokritou and Phoebe A Stapleton
    Citation: Particle and Fibre Toxicology 2023 20:16
  20. Microbial dysbiosis is a potential mediator of air pollution-induced adverse outcomes. However, a systemic comparison of the lung and gut microbiome alterations and lung-gut axis following air pollution exposu...

    Authors: Md Habibul Hasan Mazumder, Jasleen Gandhi, Nairrita Majumder, Lei Wang, Robert Ian Cumming, Sydney Stradtman, Murugesan Velayutham, Quincy A. Hathaway, Jonathan Shannahan, Gangqing Hu, Timothy R. Nurkiewicz, Robert M. Tighe, Eric E. Kelley and Salik Hussain
    Citation: Particle and Fibre Toxicology 2023 20:15
  21. The biological effects of cerium dioxide nanoparticles (CeO2NPs), a novel material in the biomedical field, have attracted widespread attention. Our previous study confirmed that exposure to CeO2NPs during pregna...

    Authors: Hangtian Zhong, Yanqing Geng, Rufei Gao, Jun Chen, Zhuxiu Chen, Xinyi Mu, Yan Zhang, Xuemei Chen and Junlin He
    Citation: Particle and Fibre Toxicology 2023 20:14
  22. As one of the environmental risk factors for human health, atmospheric fine particulate matter (PM2.5) contributes to cognitive deterioration in addition to respiratory and cardiovascular injuries. Recently, incr...

    Authors: Yanwen Hou, Wei Yan, Lin Guo, Guangke Li and Nan Sang
    Citation: Particle and Fibre Toxicology 2023 20:13
  23. Synthetic amorphous silica nanoparticles (SAS-NPs) are widely employed in pharmaceutics, cosmetics, food and concretes. Workers and the general population are exposed daily via diverse routes of exposure. SAS-...

    Authors: Éléonore Guillet, Émilie Brun, Céline Ferard, Kévin Hardonnière, Myriam Nabhan, François-Xavier Legrand, Marc Pallardy and Armelle Biola-Vidamment
    Citation: Particle and Fibre Toxicology 2023 20:12
  24. Interactions between air pollution and infectious agents are increasingly recognized and critical to identify, especially to protect vulnerable populations. Pregnancy represents a vulnerable period for influen...

    Authors: Nicholas L. Drury, Toriq Mustapha, Ross A. Shore, Jiayun Zhao, Gus A. Wright, Aline Rodrigues Hoffmann, Susanne U. Talcott, Annette Regan, Robert M. Tighe, Renyi Zhang and Natalie M. Johnson
    Citation: Particle and Fibre Toxicology 2023 20:11
  25. Pre-existing metabolic diseases may predispose individuals to particulate matter (PM)-induced adverse health effects. However, the differences in susceptibility of various metabolic diseases to PM-induced lung...

    Authors: Shen Chen, Miao Li, Rui Zhang, Lizhu Ye, Yue Jiang, Xinhang Jiang, Hui Peng, Ziwei Wang, Zhanyu Guo, Liping Chen, Rong Zhang, Yujie Niu, Michael Aschner, Daochuan Li and Wen Chen
    Citation: Particle and Fibre Toxicology 2023 20:10
  26. Toxicokinetics of nanomaterials, including studies on the absorption, distribution, metabolism, and elimination of nanomaterials, are essential in assessing their potential health effects. The fate of nanomate...

    Authors: Philku Lee, Jin Kwon Kim, Mi Seong Jo, Hoi Pin Kim, Kangho Ahn, Jung Duck Park, Mary Gulumian, Günter Oberdörster and Il Je Yu
    Citation: Particle and Fibre Toxicology 2023 20:9
  27. Montmorillonite (Mt) and its derivatives are now widely used in industrial and biomedical fields. Therefore, safety assessments of these materials are critical to protect human health after exposure; however, ...

    Authors: Jia Liu, Shubin Yang, Laien Zhao, Feng Jiang, Jianchao Sun, Shengjun Peng, Ruikang Zhao, Yanmei Huang, Xiaoxuan Fu, Rongrui Luo, Yu Jiang, Zelin Li, Nan Wang, Tengzheng Fang and Zhuhong Zhang
    Citation: Particle and Fibre Toxicology 2023 20:8
  28. Air pollution has emerged as an unexpected risk factor for diabetes. However, the mechanism behind remains ill-defined. So far, the lung has been considered as the main target organ of air pollution. In contra...

    Authors: Angela J. T. Bosch, Theresa V. Rohm, Shefaa AlAsfoor, Andy J. Y. Low, Lena Keller, Zora Baumann, Neena Parayil, Marc Stawiski, Leila Rachid, Thomas Dervos, Sandra Mitrovic, Daniel T. Meier and Claudia Cavelti-Weder
    Citation: Particle and Fibre Toxicology 2023 20:7
  29. A recent epidemiological study showed that air pollution is closely involved in the prognosis of ischemic stroke. We and others have reported that microglial activation in ischemic stroke plays an important ro...

    Authors: Miki Tanaka, Tomoaki Okuda, Kouichi Itoh, Nami Ishihara, Ami Oguro, Yoshiaki Fujii-Kuriyama, Yu Nabetani, Megumi Yamamoto, Christoph F. A. Vogel and Yasuhiro Ishihara
    Citation: Particle and Fibre Toxicology 2023 20:6
  30. Toxicity assessment for regulatory purposes is starting to move away from traditional in vivo methods and towards new approach methodologies (NAM) such as high-throughput in vitro models and computational tool...

    Authors: Polly McLean, William Mueller, Ilse Gosens, Flemming R. Cassee, Barbara Rothen-Rutishauser, Matthew Boyles and Lang Tran
    Citation: Particle and Fibre Toxicology 2023 20:5
  31. Acute phase response (APR) is characterized by a change in concentration of different proteins, including C-reactive protein and serum amyloid A (SAA) that can be linked to both exposure to metal oxide nanomat...

    Authors: Claudia Torero Gutierrez, Charis Loizides, Iosif Hafez, Anders Brostrøm, Henrik Wolff, Józef Szarek, Trine Berthing, Alicja Mortensen, Keld Alstrup Jensen, Martin Roursgaard, Anne Thoustrup Saber, Peter Møller, George Biskos and Ulla Vogel
    Citation: Particle and Fibre Toxicology 2023 20:4
  32. Nano- and microplastic particles (NMP) are strong environmental contaminants affecting marine ecosystems and human health. The negligible use of biodegradable plastics and the lack of knowledge about plastic u...

    Authors: Anke Schmidt, Walison Augusto da Silva Brito, Debora Singer, Melissa Mühl, Julia Berner, Fariba Saadati, Christina Wolff, Lea Miebach, Kristian Wende and Sander Bekeschus
    Citation: Particle and Fibre Toxicology 2023 20:3
  33. Polypropylene (PP) is used in various products such as disposable containers, spoons, and automobile parts. The disposable masks used for COVID-19 prevention mainly comprise PP, and the disposal of such masks ...

    Authors: Jong-Hwan Woo, Hyeon Jin Seo, Jun-Young Lee, Iljung Lee, Kisoo Jeon, Bumseok Kim and Kyuhong Lee
    Citation: Particle and Fibre Toxicology 2023 20:2
  34. Adverse outcome pathways (AOPs) are conceptual frameworks that organize knowledge about biological interactions and toxicity mechanisms. They present a sequence of events commencing with initial interaction(s)...

    Authors: Ozge Kose, Paride Mantecca, Anna Costa and Marie Carrière
    Citation: Particle and Fibre Toxicology 2023 20:1
  35. Many studies have shown that occupational exposure to indium and its compounds could induce lung disease. Although animal toxicological studies and human epidemiological studies suggest indium exposure may cau...

    Authors: Nan Liu, Yi Guan, Yan Yu, Gai Li, Ling Xue, Weikang Li, Xiaoyu Qu, Ning Li and Sanqiao Yao
    Citation: Particle and Fibre Toxicology 2022 19:69
  36. Nanomaterials can exist in different nanoforms (NFs). Their grouping may be supported by the formulation of hypotheses which can be interrogated via integrated approaches to testing and assessment (IATA). IATA...

    Authors: Luisana Di Cristo, Victor C. Ude, Georgia Tsiliki, Giuseppina Tatulli, Alessio Romaldini, Fiona Murphy, Wendel Wohlleben, Agnes G. Oomen, Pier P. Pompa, Josje Arts, Vicki Stone and Stefania Sabella
    Citation: Particle and Fibre Toxicology 2022 19:68
  37. The impacts of air pollution on public health have become a great concern worldwide. Ambient particulate matter (PM) is a major air pollution that comprises a heterogeneous mixture of different particle sizes ...

    Authors: Tianyu Li, Yang Yu, Zhiwei Sun and Junchao Duan
    Citation: Particle and Fibre Toxicology 2022 19:67
  38. Traffic-related air pollution (TRAP) exposure causes adverse effects on wellbeing and quality of life, which can be studied non-invasively using self-reported symptoms. However, little is known about the effec...

    Authors: Juma Orach, Christopher Francis Rider, Agnes Che Yan Yuen and Christopher Carlsten
    Citation: Particle and Fibre Toxicology 2022 19:66
  39. Exposure to particulate matter air pollution is associated with an increased risk of cardiovascular mortality in patients with chronic obstructive pulmonary disease (COPD), but the underlying mechanisms are no...

    Authors: Teng Wang, Xi Chen, Haonan Li, Wu Chen, Yifan Xu, Yuan Yao, Hanxiyue Zhang, Yiqun Han, Lina Zhang, Chengli Que, Jicheng Gong, Xinghua Qiu and Tong Zhu
    Citation: Particle and Fibre Toxicology 2022 19:65
  40. Airborne fine particulate matter with aerodynamic diameter ≤ 2.5 μm (PM2.5) pollution is associated with the prevalence of respiratory diseases, including asthma, bronchitis and chronic obstructive pulmonary dise...

    Authors: Junling Gao, Tong Lei, Hongyun Wang, Kai Luo, Yuanli Wang, Bingqing Cui, Zhuoran Yu, Xiaoqi Hu, Fang Zhang, Yingjie Chen, Wenjun Ding and Zhongbing Lu
    Citation: Particle and Fibre Toxicology 2022 19:64
  41. The toxicokinetic behaviour of nanostructured particles following pulmonary or oral deposition is of great scientific interest. In this toxicokinetic study, following the general principles of OECD TG 417, the...

    Authors: Otto Creutzenberg, Volker Hammann, Stefanie Wolf, Jürgen Daul, Yufanyi Ngiewih, Ishrat Chaudhuri and Len Levy
    Citation: Particle and Fibre Toxicology 2022 19:63
  42. A key aspect of any new material safety assessment is the evaluation of their in vivo genotoxicity. Graphene oxide (GO) has been studied for many promising applications, but there are remaining concerns about ...

    Authors: Luis Augusto Visani de Luna, Thomas Loret, Alexander Fordham, Atta Arshad, Matthew Drummond, Abbie Dodd, Neus Lozano, Kostas Kostarelos and Cyrill Bussy
    Citation: Particle and Fibre Toxicology 2022 19:62
  43. Exposure to air pollutants is one of the major environmental health risks faced by populations globally. Information about inhaled particle deposition dose is crucial in establishing the dose–response function...

    Authors: Leizel Madueño, Simonas Kecorius, Jakob Löndahl, Jürgen Schnelle-Kreis, Alfred Wiedensohler and Mira Pöhlker
    Citation: Particle and Fibre Toxicology 2022 19:61
  44. Microplastics (MPs) and nanoplastics (NPs) formed from decomposed plastic are increasing environmental threats. Although MPs and NPs exposed through various routes enter the systemic circulation, the potential...

    Authors: Eun-Hye Kim, Sungbin Choi, Donghyun Kim, Han Jin Park, Yiying Bian, Sang Ho Choi, Han Young Chung and Ok-Nam Bae
    Citation: Particle and Fibre Toxicology 2022 19:60
  45. The number of publications in the field of nanogenotoxicology and the amount of genotoxicity data on nanomaterials (NMs) in several databases generated by European Union (EU) funded projects have increased dur...

    Authors: Kirsi M. Siivola, Michael J. Burgum, Blanca Suárez-Merino, Martin J. D. Clift, Shareen H. Doak and Julia Catalán
    Citation: Particle and Fibre Toxicology 2022 19:59

    The Correction to this article has been published in Particle and Fibre Toxicology 2022 19:70

  46. Most toxicological studies on titanium dioxide (TiO2) particles to date have concentrated on carcinogenicity and acute toxicity, with few studies focusing of pneumoconiosis, which is a variety of airspace and int...

    Authors: Shotaro Yamano, Yuko Goto, Tomoki Takeda, Shigeyuki Hirai, Yusuke Furukawa, Yoshinori Kikuchi, Tatsuya Kasai, Kyohei Misumi, Masaaki Suzuki, Kenji Takanobu, Hideki Senoh, Misae Saito, Hitomi Kondo and Yumi Umeda
    Citation: Particle and Fibre Toxicology 2022 19:58
  47. Over the last two decades, nanotechnologies and the use of nanoparticles represent one of the greatest technological advances in many fields of human activity. Particles of titanium dioxide (TiO2) are one of the ...

    Authors: Eloïse Colnot, Laura Cardoit, Marie-Jeanne Cabirol, Lydia Roudier, Marie-Helene Delville, Anne Fayoux, Muriel Thoby-Brisson, Laurent Juvin and Didier Morin
    Citation: Particle and Fibre Toxicology 2022 19:57
  48. Air pollution has been associated with neurodevelopmental disorders in epidemiological studies. In our studies in mice, developmental exposures to ambient ultrafine particulate (UFP) matter either postnatally ...

    Authors: Marissa Sobolewski, Katherine Conrad, Elena Marvin, Matthew Eckard, Calla M. Goeke, Alyssa K. Merrill, Kevin Welle, Brian P. Jackson, Robert Gelein, David Chalupa, Günter Oberdörster and Deborah A. Cory-Slechta
    Citation: Particle and Fibre Toxicology 2022 19:56

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