| |
Study day 7
|
Study day 28
|
|---|
|
Concentration [mg/m3]
|
0.1
|
0.5
|
2.5
|
0.1
|
0.5
|
2.5
|
|
β2-Microglobulin
|
1.1
|
1.6**
|
2.8**
|
1.1
|
1.2
|
2.2**
|
|
CINC-1/IL-8
|
1.0
|
4.6**
|
13.3**
|
1.2
|
2.1*
|
10.5**
|
|
Clusterin
|
1.5
|
1.9*
|
4.4**
|
1.0
|
1.1
|
2.2*
|
|
GCP-2
|
0.9
|
8.1**
|
19.9**
|
1.6
|
4.0*
|
36.2**
|
|
KC/GROα
|
1.5
|
6.3*
|
36.9**
|
0.7
|
1.6
|
20.8**
|
|
MCP-1
|
1.0
|
2.3**
|
15.8**
|
1.5
|
1.6*
|
13.5**
|
|
MCP-3
|
1.0
|
2.5**
|
22.3**
|
1.6
|
1.7*
|
15.9**
|
|
M-CSF
|
1.4
|
4.3**
|
9.6**
|
1.1
|
1.7*
|
3.7**
|
|
MDC
|
1.2
|
6.1
|
50.8**
|
1.1
|
1.8
|
20.6**
|
|
MIP-1β
|
0.7
|
1.2
|
3.1**
|
1.6
|
1.5
|
4.1**
|
|
MIP-2
|
1.1
|
2.6**
|
4.5**
|
1.5
|
1.7*
|
5.4**
|
|
MPO
|
1.6
|
29.5*
|
193.3**
|
1.4
|
1.9
|
65.5**
|
|
VEGF
|
1.1
|
2.1*
|
5.0**
|
1.0
|
1.0
|
1.6
|
- * Statistically significant, p < 0.05; ** statistically significant, p < 0.01.
- Differences are expressed as x-fold ratios compared to the concurrent control group.
