Figure 8

Interaction of GO nanoplatelets with the plasma membrane of Hep G2 cells. A) SEM micrograph showing the interaction of GO nanoplatelets (exemplarily indicated by black arrows) with the plasma membrane (pm) and microvilli (mv). B) SEM micrographs showing the boxed-in area in A at higher magnification. GO nanoplatelet penetrating the plasma membrane (arrow with white asterisk). C) Membrane invagination (white arrow) at the site of interaction of a GO nanoplatelet (black arrow) with the plasma membrane. D) Disruption of the plasma membrane (black asterisk) at the site of interaction with GO nanoplatelets (exemplarily indicated by black arrows). Scale bars represent 200 nm in A and B, and 500 nm in C and D. Black arrows exemplarily indicate GO nanoplatelets. mt: mitochondrion, pm: plasma membrane, mv: microvilli.