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Table 2 Characteristics of the repetitive element subfamilies examined in the present study

From: Evolutionary age of repetitive element subfamilies and sensitivity of DNA methylation to airborne pollutants

Repetitive element Evolutionary age (Mya) a CpG density (CpG o/e) b Mean methylation (%) c
Family Subfamily    
  L1PA5 20.4 0.073 25.3
LINE-1 L1PA2 7.6 0.104 70.6
  L1Hs 5 0.155 79.5
  L1Ta 1.9 0.282 70.1
  Alu Sx 40 0.878 24.7
Alu Alu Yb8 2.9 0.884 89.9
  Alu Yd6 2 0.95 89.9
  MLT1D 98.2 0.043 97.9
HERV ERV1 24.4 0.074 24.5
  ERV9 15 0.439 52
  1. a Estimated time in ‘Million years ago’ (Mya) based on the time when the repetitive element subfamily appeared in the human genome.
  2. b Approximate ratio of the observed to the expected CpG content (CpGo/e) of the sequence. CpG observed/expected (CpGo/e). The ratio is calculated using the formula ((Num of CpG/(Num of C × Num of G)) × Total number of nucleotides in the sequence).
  3. c Mean methylation of all low-exposure control groups from Study 1, Study 2, and Study 3.