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Figure 2 | Particle and Fibre Toxicology

Figure 2

From: An improved 3D tetraculture system mimicking the cellular organisation at the alveolar barrier to study the potential toxic effects of particles on the lung

Figure 2

Colonies of differentiated THP- 1 cells on top of epithelial A549 cells. A: Analysis of the distribution of THP-1 cells in the coculture system by a z-stack image series. THP-1 cells form colonies of several cells on top of A549 cells. THP-1 cells are stained with anti-CD11b-antibody (green); nuclei are counterstained with DAPI (blue). X–y projection with the respective side views (Magnification: 630x). B: Same image as shown in A but only with the channels for DAPI and CD11b. The red arrows indicate representative colonies (Magnification: 630x).

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