Ultrastructure of kidney in male mice
caused by intragastric administration of TiO
NPs for 90 consecutive days.
(a) Control, (b) 2.5 mg/kg TiO2 NPs, (c) 5 mg/kg TiO2 NPs,
(d) 10 mg/kg
TiO2 NPs. Yellow arrows indicate nucleus
shrinkage, chromatin marginalization, green arrows indicate mitochondria
swelling, and red arrows show presence of TiO2 NPs.
Arrow A spot is a representative cell that not engulfed the
TiO2 NPs, while arrow B spot denotes a
representative cell that loaded with TiO2 NPs. The
right panels show the corresponding Raman spectra identifying the specific
peaks at about 148 cm-1.