Figure 7
In vivo lung fibrotic response to several MWCNT and crocidolite. (A) Hydroxyproline lung content and cytokine levels in BALF, (B) total TGF-β1, (C) PDGF-BB and (D) OPN (quantified by ELISA) were measured 2 months after pharyngeal aspiration of MWCNT (NM400, NM400c, MWCNTg 2400) and crocidolite in C57BL/6 mice. Min-U-Sil (SiO2) was used as positive control. * p < 0.05, ** p < 0.01, *** p < 0.001 vs non-treated mice (n = 5-8, t-test).