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Figure 3 | Particle and Fibre Toxicology

Figure 3

From: Effect of MWCNT size, carboxylation, and purification on in vitro and in vivo toxicity, inflammation and lung pathology

Figure 3

Cell viability data and IL-1b release for THP-1 cells exposed to various MWCNT for 24 hours. Data expressed as mean ± SEM percent viable cells compared to no particle control condition for A - C. Data expressed as mean ± SEM pg/ml IL-1β for D – F. A) Cell viability for the 3 variants of the narrow/short MWCNT. B) Cell viability for the 3 variants of the wide/short MWCNT. C) Cell viability for the 3 variants of the narrow/long MWCNT. D) IL-1β release for the 3 variants of the narrow/short MWCNT. E) IL-1β release for the 3 variants of the wide/short MWCNT. F) IL-1β release for the 3 variants of the narrow/long MWCNT. Asterisks indicate significance *** at P < 0.001, ** at P < 0.01, * at P < 0.05 compared to functionalized MWCNT variant at the same concentration. Daggers indicate significance ††† at P < 0.001, †† at P < 0.01, † at P < 0.05 compared to the 0 μg/ml no particle control.

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