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Table 2 Changes in the hematological indices in all subjects exposed to DE and Filtered Air (FA)

From: A randomized cross-over study of inhalation of diesel exhaust, hematological indices, and endothelial markers in humans

Hematological indices n Change from baseline to 7 h Mean ± SE DE effect Δ baseline - 7 h (95% CI) n Change from baseline to 22 h Mean ± SE DE effect Δ baseline - 22 h (95% CI)
Filtered air DE-200 Filtered air DE-200
Leukocytes (x1000 cells/μL) 26 0.4 ± 0.2 0.4 ± 0.2 -0.0 (-0.3 to 0.3) 24 0.03 ± 0.1 0.1 ± 0.2 0.1 (-0.3 to 0.4)
Neutrophils (x1000 cells/μL) 24 0.4 ± 0.1 0.5 ± 0.2 0.0 (-0.4 to 0.4) 24 0.2 ± 0.1 0.2 ± 0.1 0.1 (-0.3 to 0.4)
Lymphocytes (x1000 cells/μL) 25 0.03 ± 0.1 -0.01 ± 0.1 -0.04 (-0.2 to 0.1) 23 -0.1 ± 0.05 -0.1 ± 0.04 -0.03 (-0.2 to 0.1)
Monocytes (x1000 cells/μL) 24 0.01 ± 0.02 -0.01 ± 0.03 -0.02 (-0.1 to 0.1) 21 -0.03 ± 0.02 -0.002 ± 0.04 0.03 (-0.1 to 0.1)
Erythrocytes (million cells/μL) 30 0.1 ± 0.02 -0.2 ± 0.2 -0.2 (-0.7 to 0.2) 28 0.1 ± 0.03 0.2 ± 0.3 0.1 (-0.5 to 0.7)
Platelets (x1000 cells/μL) 24 9.2 ± 3.4 11.4 ± 2.8 2.2 (-4.2 to 8.7) 22 4.5 ± 2.9 10.1± 2.6 5.5 (-2.8 to 13.8)
Hemoglobin (gm/dL) 24 0.2 ± 0.1 0.3 ± 0.1 0.2 (-0.0 to 0.4) 24 0.3 ± 0.1 0.5 ± 0.1 0.1 (-0.1 to 0.4)
Hematocrit (%) 26 0.5 ± 0.3 1.4 ± 0.2 1 (0.3 to 1.6)* 23 1.6 ± 0.4 1.1 ± 0.3 0.5 (-0.5 to 1.4)
  1. Data are shown for the absolute mean differences from pre-exposure to 7 hours (Δ Baseline-7 h) and 22 hours (Δ Baseline-22 h) of exposure initiation. DE effect refers to the effect attributable to DE calculated as [(Post –pre DE exposure - (Post-pre) FA exposure] displayed as the absolute change in each of the indices.
  2. *Indicates a P-value of 0.008; SE represents standard error; CI – Confidence Interval.