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Table 3 Total number of cells, total protein concentration and activity of LDH in BAL fluid in shams and ZnO NP-exposed mice (sub-acute study)

From: Toxicity assessment of zinc oxide nanoparticles using sub-acute and sub-chronic murine inhalation models

Sub-acute study   Experimental group:
Parameter in BAL fluid Sentinels Shams ZnO ZnO
(n = 2) 0 wk 0 wk 3 wks
  (n = 6) (n = 6) (n = 6)
Total cells/mouse, n × 103 105.0 ± 27.0 92.7 ± 8.6 150.3 ± 14.9** 67.0 ± 11.2
Total protein, μg/mL 122.2 ± 2.9 135.5 ± 6.8 125.5 ± 4.1 131.3 ± 5.8
LDH activity, U/L 63 ± 18 46 ± 4 32 ± 9 93 ± 23**
  1. Values are expressed as mean and SE; **p < 0.01 significantly different from sham-exposed animals (one way ANOVA).