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Table 6 Blood parameters in shams and mice after sub-chronic exposure to ZnO NPs

From: Toxicity assessment of zinc oxide nanoparticles using sub-acute and sub-chronic murine inhalation models

Whole blood parameter   Experimental group:
Sentinels Shams 0 wk ZnO 0 wk ZnO 3 wks
WBC × 103/μL 3.62 ± 0.5 4.18 ± 0.6 3.79 ± 1.0 4.90 ± 0.4
RBC × 106/μL 9.66 ± 0.2 9.20 ± 0.2 9.6 ± 0.4 9.63 ± 0.3
Hemoglobin, g/dL 15.4 ± 0.2 16.0 ± 0.2 16.2 ± 0.4 16.2 ± 0.2
Hematocrit,% 50.2 ± 0.7 45.0 ± 0.6 47.8 ± 0.3 52.9 ± 1.7
Monocytes × 103/μL 0.34 ± 0.1 0.22 ± 0.1 0.24 ± 0.1 0.20 ± 0.3
Neutrophils × 103/μL 2.11 ± 0.5 0.92 ± 0.2 1.29 ± 0.3 1.9 ± 0.2
Lymphocytes × 103/μL 1.14 ± 0.2 2.98 ± 0.4 2.20 ± 0.9 2.75 ± 0.4
Eosinophils × 103/μL 0.032 ± 0.010 0.055 ± 0.013 0.062 ± 0.035 0.074 ± 0.013
Basophils × 103/μL 0.002 ± 0.001 0.013 ± 0.003 0.013 ± 0.004 0.008 ± 0.003
  1. Values are expressed as mean and SE, WBC - white blood cells, RBC - red blood cells, n = 6 in each group.