Figure 8

Effects of PM _2.5 exposure on inflammation, insulin and MAPK signaling pathways in the liver of KKay mice. (A-C), Western blotting for phosphorylated AKT (P-AKT)/total AKT (A), PI3K (B), and phosphorylated AMPK (P-AMPK)/total AMPK (C). n = 3-7 per group. (D), Representative image and analysis of F4/80⁺ staining by immunohistochemistry. n = 14-21 sections from 7–8 mice. (E-G), Western blotting of signaling molecules involved in MAPK pathway [P-p38/p38, (E); P-ERK/ERK, (F); P-JNK/JNK, (G)]. n = 3-7 per group. *P < 0.05 compared to respective FA group.