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Table 3 Silica content in tissues in mg silica/kg tissue (mean ± standard error of the mean, n=5) after 84 days of exposure

From: Sub-chronic toxicity study in rats orally exposed to nanostructured silica

 

SAS high

NM-202 high

Control

Liver

78 ± 2

<75*

<75*

Kidney

79 ± 4

<75*

<75*

Spleen

248 ± 81a,b

<75*

<75*b

Brain

100 ± 23

<75*

<75*

Testis

105 ± 17

<75*

87 ± 12

  1. aSignificant increase versus control, or bversus the results from the corresponding group after 28-days of exposure (p<0.05). * Measurements were below the limit of detection and were therefore set at the limit of detection of 75 mg silica/kg tissue.
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Particle and Fibre Toxicology

ISSN: 1743-8977

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