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Table 3 Silica content in tissues in mg silica/kg tissue (mean ± standard error of the mean, n=5) after 84 days of exposure

From: Sub-chronic toxicity study in rats orally exposed to nanostructured silica

  SAS high NM-202 high Control
Liver 78 ± 2 <75* <75*
Kidney 79 ± 4 <75* <75*
Spleen 248 ± 81a,b <75* <75*b
Brain 100 ± 23 <75* <75*
Testis 105 ± 17 <75* 87 ± 12
  1. aSignificant increase versus control, or bversus the results from the corresponding group after 28-days of exposure (p<0.05). * Measurements were below the limit of detection and were therefore set at the limit of detection of 75 mg silica/kg tissue.