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Figure 1 | Particle and Fibre Toxicology

Figure 1

From: Single-Walled Carbon Nanotube (SWCNT)-induced interstitial fibrosis in the lungs of rats is associated with increased levels of PDGF mRNA and the formation of unique intercellular carbon structures that bridge alveolar macrophages In Situ

Figure 1

Lung histopathology from rats 21 days after a single oropharyngeal aspiration exposure to saline vehicle containing 0.1% Pluronic F-68 (A, B), carbon black ultrafine particles (C, D), aggregates of single walled carbon nanotubes, SWCNT (E, F), or vanadium pentoxide (V2O5) (G, H). Carbon inclusions are indicated by closed arrows in panels C, D, and F. Regions of alveolar wall thickening in the lungs of rats exposed to SWCNT are indicated by open arrows adjacent to carbon-filled macrophages in panesl E and F. Original magnification 20× (panels A, C, E, G) or 40× (panels B, D, F, H).

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Particle and Fibre Toxicology

ISSN: 1743-8977

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