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Figure 1 | Particle and Fibre Toxicology

Figure 1

From: Pulmonary toxicity screening studies in male rats with TiO2 particulates substantially encapsulated with pyrogenically deposited, amorphous silica

Figure 1

Pulmonary inflammation in particulate-exposed rats and controls as evidenced by % neutrophils (PMN) in BAL fluids at 24 hrs, 1 week, 1 month and 3 months postexposure (pe). Values given are means ± S.D. Intratracheal instillation exposures of several particle-types produced a short-term, pulmonary inflammatory response, as evidenced by an increase in the percentages/numbers of BAL-recovered neutrophils, measured at 24 hrs postexposure. However, only the exposures to quartz particles (1 and 5 mg/kg) produced sustained pulmonary inflammatory responses, as measured through 3 months postexposure. *p < 0.05.

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Particle and Fibre Toxicology

ISSN: 1743-8977

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