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Figure 2 | Particle and Fibre Toxicology

Figure 2

From: Pulmonary toxicity screening studies in male rats with TiO2 particulates substantially encapsulated with pyrogenically deposited, amorphous silica

Figure 2

BAL fluid LDH values for particulate-exposed rats and corresponding controls at 24 hrs, 1 week, 1 month and 3 months postexposure (pe). Values given are means ± S.D. Transient and reversible increases in BAL fluid lactate dehydrogenase values were measured in the lungs of high dose (5 mg/kg) R-100 TiO2-exposed rats at 1 week postexposure. In contrast, exposures to 5 mg/kg quartz particles produced a sustained increase in BAL fluid LDH values through the 3-month postexposure period. *p < 0.05.

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