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Table 2 Geometric means (95% CI) of all dependent variables according to exposure, time and activity

From: Exposure to ambient concentrations of particulate air pollution does not influence vascular function or inflammatory pathways in young healthy individuals

 

Time of exposure

All

Cycling

Rest

  

Non-filtered

Filtered

Non-filtered

Filtered

Non-filtered

Filtered

MVF scorea

6 h

2.17(2.04, 2.30)

2.20(2.07, 2.34)

2.18(2.01, 2.36)

2.14(1.99, 2.31)

2.15(1.95, 2.37)

2.26(2.03, 2.50)

 

24 h

2.12(2.00, 2.25)

2.04(1.92, 2.16)

2.09(1.89, 2.30)

1.98(1.81, 2.15)

2.16(2.01, 2.31)

2.10(1.92, 2.29)

Haemoglobin (mmol/L)

6 h

8.84(8.64, 9.05)

8.86(8.67, 9.06)

8.83(8.52, 9.14)

8.78(8.51, 9.05)

8.85(8.56, 9.15)

8.95(8.67, 9.25)

 

24 h

8.81(8.62, 9.01)

8.82(8.63, 9.01)

8.71(8.43, 9.00)

8.70(8.44, 8.96)

8.91(8.64, 9.20)

8.94(8.66, 9.23)

Red blood cells (×1012/L)

6 h

4.79(4.70, 4.88)

4.80(4.71, 4.88)

4.78(4.64, 4.92)

4.75(4.64, 4.87)

4.80(4.68, 4.92)

4.85(4.72, 4.98)

 

24 h

4.78(4.70, 4.87)

4.78(4.70, 4.87)

4.74(4.61, 4.87)

4.73(4.61, 4.85)

4.84(4.72, 4.95)

4.84(4.71, 4.97)

Fibrinogen (μmol/L)

6 h

9.0(8.8, 9.3)

9.2(9.0, 9.5)

9.1(8.7, 9.5)

9.2(8.8, 9.5)

9.0(8.6, 9.4)

9.3(8.9, 9.7)

 

24 h

9.2(8.9, 9.5)

9.2(8.9, 9.5)

9.3(9.0, 9.7)

9.1(8.7, 9.6)

9.1(8.6, 9.6)

9.3(8.9, 9.6)

Platelets (×109/L)

6 h

248(234, 264)

249(236, 264)

250(228, 273)

248(230, 268)

247(227, 269)

250(230, 273)

 

24 h

240(226, 254)

241(228, 255)

242(223, 263)

240(222, 259)

237(217, 259)

243(223, 264)

CF (II+VII+X)b

6 h

1.02(0.98, 1.05)

1.03(1.00, 1.06)

1.02(0.97, 1.07)

1.04(1.00, 1.09)

1.01(0.97, 1.06)

1.02(0.98, 1.07)

 

24 h

1.02(0.99, 1.06)

1.03(1.00, 1.06)

1.02(0.98, 1.07)

1.02(0.98, 1.07)

1.03(0.98, 1.07)

1.04(0.99, 1.08)

C-reactive protein (mg/L)

6 h

1.3(1.1, 1.5)

1.5(1.3, 1.8)

1.2(1.0, 1.4)

1.5(1.2, 2.0)

1.3(1.0, 1.8)

1.5(1.1, 1.9)

 

24 h

1.4(1.2, 1.7)

1.5(1.2, 1.7)

1.5(1.2, 1.9)

1.6(1.3, 2.1)

1.3(1.0, 1.8)

1.3(1.0, 1.7)

Interleukin-6 (ng/L)

6 h

0.83(0.72, 0.95)

0.91(0.79, 1.05)

0.89(0.73, 1.08)

1.02(0.86, 1.20)

0.77(0.63, 0.94)

0.81(0.64, 1.03)

 

24 h

0.91(0.76, 1.07)

0.83(0.70, 0.98)

0.84(0.69, 1.02)

0.90(0.70, 1.16)

0.98(0.73, 1.31)

0.76(0.61, 0.96)

TNF-α (ng/L)c

6 h

1.09(1.00, 1.20)

1.14(1.05, 1.24)

1.12(0.97, 1.28)

1.20(1.06, 1.35)

1.07(0.94, 1.22)

1.08(0.96, 1.21)

 

24 h

1.17(1.06, 1.28)

1.17(1.08, 1.27)

1.20(1.08, 1.34)

1.19(1.06, 1.34)

1.13(0.97, 1.33)

1.15(1.01, 1.30)

PLAAS (pmol/mg)d

6 h

41.1(39.1, 43.1)

41.7(39.6, 43.8)

41.4(38.9, 44.1)

43.9(40.9, 47.1)

40.7(37.6, 44.0)

39.5(36.7, 42.5)

 

24 h

41.3(38.9, 43.9)

42.5(39.9, 45.3)

41.4(37.6, 45.6)

43.4(39.3, 48.0)

41.2(38.0, 44.8)

41.6(38.3, 45.2)

AAPH (lagtime min)e

6 h

238(225, 251)

234(223, 245)

237(218, 257)

238(222, 255)

238(222, 257)

229(215, 245)

 

24 h

236(225, 247)

232(221, 243)

234(221, 249)

235(220, 250)

237(220, 255)

229(212, 246)

  1. aMicrovascular function: a detailed description of the score and its relation to endothelial function is provided in the methods section
  2. bCoagulation factor
  3. cTumour necrosis factor α
  4. d2-aminoapidic semialdehyde in plasma proteins (pmol/mg protein)
  5. eSusceptibility to lipoprotein oxidation in plasma was measured as lagtime (min) of ex vivo oxidation with AAPH (2,2'-azobis(2 aminopropane)dihydrochloride)
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Particle and Fibre Toxicology

ISSN: 1743-8977

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